myositis/kalium

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Peripheral G protein-coupled inwardly rectifying potassium channels are involved in δ-opioid receptor-mediated anti-hyperalgesia in rat masseter muscle.

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BACKGROUND Although the efficacy of peripherally administered opioid has been demonstrated in preclinical and clinical studies, the underlying mechanisms of its anti-hyperalgesic effects are poorly understood. G protein-coupled inwardly rectifying potassium (GIRK) channels are linked to opioid

Acute kidney injury due to rhabdomyolysis-associated gangrenous myositis.

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Rhabdomyolysis is associated with infectious diseases in approximately 5% of cases and acute kidney injury occurs in 33-50% of cases. Gangrenous myositis is a deep seated infection of the subcutaneous and muscular tissues. We report the case of an 18 year-old man who was admitted to the emergency

Autoantibodies in thymoma-associated myasthenia gravis with myositis or neuromyotonia.

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BACKGROUND About 50% of patients with thymoma have paraneoplastic myasthenia gravis (MG). Myositis and myocarditis or neuromyotonia (NMT) will also develop in some. Patients with thymoma-associated MG produce autoantibodies to a variety of neuromuscular antigens, particularly acetylcholine receptor

Acute Neuromuscular Disorders in the Pediatric Intensive Care Unit.

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The neuromuscular disorders encountered in the pediatric intensive care unit (PICU) encompass a broad spectrum of pathologies. These include acute disorders (eg, Guillain-Barre syndrome), acute-on-chronic disorders (eg, myasthenia gravis), progressive disorders (eg, muscular

Equine postanesthetic forelimb lameness: intracompartmental muscle pressure changes and biochemical patterns.

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Intracompartmental muscle pressures were recorded from the right and left forelimbs (extensor carpi radialis, triceps brachii) of healthy horses maintained in left lateral recumbency while under deep halothane anesthesia for 180 to 240 minutes. Cardiac output, blood pressure, blood gases, and

Sweet's syndrome from an Indian perspective: a report of four cases and review of the literature.

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BACKGROUND Sweet's syndrome or acute febrile neutrophilic dermatosis is not frequently reported from India. Four patients fulfilling clinico-pathologic criteria for Sweet's syndrome seen during May-August 2002 prompted us to review reports on Indian patients from the indexed literature. METHODS A

[New clinical entity of myasthenia gravis with autoimmune targets of heart and skeletal muscles].

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Since previous case reports have shown inflammatory myopathies in a few patients with myasthenia gravis (MG), heart and skeletal muscles are speculated to be autoimmune targets in MG. We screened to investigate the clinical, histological and immunological features of MG patients, who also developed

Acute neuromuscular weakness associated with dengue infection.

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BACKGROUND Dengue infections may present with neurological complications. Whether these are due to neuromuscular disease or electrolyte imbalance is unclear. METHODS Eighty-eight patients of dengue fever required hospitalization during epidemic in year 2010. Twelve of them presented with acute

Spectrum of hypokalaemic periodic paralysis in a tertiary care centre in India.

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BACKGROUND Acute flaccid paralysis is a common neurological emergency with diverse causes and variable outcome. There is a paucity of reports documenting the spectrum of hypokalaemic paralysis in neurological practice. OBJECTIVE To report the clinical features, aetiology, and outcome of patients

Profound muscle weakness and hypokalemia due to clay ingestion.

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We have presented the case of a 43-year-old woman with severe myositis due to clay ingestion and hypokalemia. EMG studies revealed a pattern consistent with myositis, and muscle biopsy showed a nonspecific diffuse myositis. The clay was shown to act as a potassium binder. With potassium replacement

Refeeding syndrome: a potentially fatal condition but remains underdiagnosed and undertreated.

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OBJECTIVE To describe two cases of successfully prevented refeeding syndrome in a high-risk group of patients. METHODS Case 1 was a 70-y-old woman who presented with a 4-mo history of poor dietary intake and ill health due to a connective tissue disease leading to myositis and dysphagia and

[Dermatomyositis and hypokalemia: a difficult diagnosis].

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The idiopathic inflammatory myopathies are systemic autoimmune diseases characterizes by chronic muscle inflammation. The frequent extramuscolar manifestations contribute to the morbidity and mortality of the disease. The goal of medical therapy is based on immune suppression with first-line agent

[Ptosis in the differential diagnosis of neurologic diseases].

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This review summarizes those neurological diseases which are accompanied by a drooping of the upper lid, due to weakness of the m. levator palpebrae or m. tarsalis respectively. After connatal ptosis with or without involvement of other bulbar muscles the different types of muscular dystrophies are

Serum creatine kinase levels and renal function measures in exertional muscle damage.

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OBJECTIVE Serum creatine kinase (CK) levels are commonly used to judge the severity of muscle damage and to determine when to hospitalize patients who present with symptoms of exertional rhabdomyolysis in order to prevent renal failure. However, no CK standard exists because of the limited

Dengue-associated neuromuscular complications.

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Dengue is associated with many neurological dysfunctions. Up to 4% of dengue patients may develop neuromuscular complications. Muscle involvement can manifest with myalgias, myositis, rhabdomyolysis and hypokalemic paralysis. Diffuse myalgia is the most characteristic neurological symptom of dengue

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