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neurodegenerative diseases/dl proline
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9 resultaten
Proline or proline derivatives for the treatment of dementia
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The invention relates to pharmaceutical composition comprising proline derivatives, preferably Cis-4-hydroxy-I-proline (CHP) and trans-4-Hydroxy-L-proline (THP), or proline, or their salts, esters, isomers, racemates, enantiomers or pro-drugs thereof, and to the use of said compositions for the
Therapeutic proline derivatives
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FIELD OF THE INVENTION
This invention relates to proline derivatives useful as pharmaceutical agents, to processes for their production, to pharmaceutical compositions containing them, and to their use for the treatment of the conditions set out below.
BACKGROUND TO THE INVENTION
Gabapentin
Co-crystal forms of a novobiocin analog and proline
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BACKGROUND
Approximately 26 million Americans are afflicted with either Type 1 or Type 2 diabetes. Despite the use of insulin and oral anti-diabetic medications to help maintain euglycemia, about 60-70% of these individuals develop diabetic peripheral neuropathy (DPN). See Veves, A.; Backonja, M.;
Structural mimetics of proline-rich peptides and the pharmaceutical use thereof
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This is the U.S. national stage of International application PCT/DE2007/001768, filed Sep. 25, 2007 designating the United States and claiming priority to European Applications EP 0609078.2, filed Sep. 25, 2006; EP 06090179.0, filed Sep. 25, 2006; and EP 07090095.6, filed May 7, 2007 and German
Mimotopes of alpha-synuclein and vaccines thereof for the treatment of neurodegenerative disorders
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CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a 35 U.S.C. .sctn.371 National Stage patent application of International patent application PCT/AT2009/000071, filed on Feb. 23, 2009, which claims priority to Austria patent application A297/2008, filed on Feb. 22, 2008.
The present
Synergistic compositions comprising ascobate and lysine for states related to extra cellular matrix degeneration
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FIELD OF INVENTION
The present invention relates to substances and compositions for the prevention and treatment of diseases or pathological states related to the degradation of the extracellular matrix, such as including but not limited to degenerative diseases, particularly arteriosclerosis,
Analogs of glycyl-prolyl-glutamate
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FIELD OF THE INVENTION
The present invention relates to novel analogs of Glycyl-Prolyl-Glutamate (GPE) and methods of their use. Additionally, this invention relates to the use of these compounds and pharmaceutical compositions thereof in the treatment of diseases and conditions characterised by
Antibodies for the selective determination of procalcitonin 1-116
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a 371 filing of PCT International application no. PCT/EP2008/001373 filed Feb. 21, 2008 and published in English as WO 2008/104321 A1 on Sep. 4, 2008, which claims the priority of German application no. 102007009751.6 filed Feb. 28, 2007.
Method for the selective detection and measurement of procalcitonin 1-116 and amino-terminal peptides of procalcitonin comprising amino acids 1 and 2 of procalcitonin 1-116
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The invention relates to the area of medical diagnosis, in particular the determination of biomarkers in biological fluids by means of immunodiagnostic methods. More precisely, the invention relates to the determination of the peptide procalcitonin for diagnostic purposes, a selective measured value
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