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neurodegenerative diseases/koorts
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Oligonucleotides which inhibit p53 induction in response to cellular stress
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FIELD OF THE INVENTION
The present invention relates to modulating the activity of p53 tumor suppressor protein by affecting p53 translational regulation and its use for minimizing the negative effects of cellular stresses. More specifically, the invention relates to novel oligonucleotides which
Methods, compositions and articles of manufacture for enhancing survivability of cells, tissues, organs, and organisms
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the field of cell biology and physiology. More particularly, it concerns methods, compositions and apparatuses for enhancing survivability of and/or reducing damage to cells, tissues, organs, and
Substituted tryptamines, phenalkylamines and related compounds
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FIELD OF THE INVENTION
This invention relates to novel substituted tryptamine and phenalkylamine and related compounds, pharmaceutical compositions thereof, and methods of using said compounds and compositions for a number of pharmaceutical indications, including (but not limited to): 1. central
Inhibitors of glutaminyl cyclase
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FIELD OF THE INVENTION
The invention relates to glutaminyl cyclase (QC, EC 2.3.2.5) that catalyzes the intramolecular cyclization of N-terminal glutamine residues into pyroglutamic acid (5-oxo-prolyl, pGlu*) under liberation of ammonia and the intramolecular cyclization of N-terminal glutamate
Inhibitors of glutaminyl cyclase
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FIELD OF THE INVENTION
The invention relates to glutaminyl cyclase (QC, EC 2.3.2.5) that catalyzes the intramolecular cyclization of N-terminal glutamine residues into pyroglutamic acid (5-oxo-prolyl, pGlu*) under liberation of ammonia and the intramolecular cyclization of N-terminal glutamate
Inhibitors of glutaminyl cyclase
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The Sequence Listing, which is a part of the present disclosure, includes a computer readable form and a written sequence listing comprising nucleotide and/or amino acid sequences of the present invention. The sequence listing information recorded in computer readable form is identical to the
Inhibitors of glutaminyl cyclase
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The Sequence Listing, which is a part of the present disclosure, includes a computer readable form and a written sequence listing comprising nucleotide and/or amino acid sequences of the present invention. The sequence listing information recorded in computer readable form is identical to the
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