pilocarpine/braken

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Effect of ablation of medullary emetic chemoreceptor trigger zone on vomiting responses to cerebral intraventricular injection of adrenaline, apomorphine and pilocarpine in the cat.

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Attempted suicide with pilocarpine eyedrops.

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OBJECTIVE To alert ophthalmologists about the hazards of poisoning with ophthalmic solutions. METHODS We treated an 18-year-old man who attempted suicide by drinking and self-injecting pilocarpine eyedrops. He had severe signs of parasympathomimetic poisoning. RESULTS Because of heavy and repeated

Post-radiation severe xerostomia relieved by pilocarpine: a prospective French cooperative study.

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OBJECTIVE The aim of the study was: (1) to confirm the action of pilocarpine hydrochloride (Salagen) against xerostomia: (2) to correlate the response to dose/volume radiotherapy parameters. METHODS From June 1995 to February 1996, 156 patients with severe radiation induced xerostomia received

Pilocarpine, a non-hallucinogenic cholinergic agonist, elicits limb flicking in cats.

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The centrally- and peripherally-acting muscarinic cholinergic agonist pilocarpine (PILO, 0.125-1.0 mg/kg, IP) elicited a significantly increased frequency of occurrence of limb flicking at 0.25-1.0 mg/kg, and significantly increased the frequency of occurrence of other grooming behaviors, in 4-6

Oral pilocarpine for the treatment of ocular symptoms in patients with Sjögren's syndrome: a randomised 12 week controlled study.

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OBJECTIVE To evaluate the efficacy and side effects of oral pilocarpine for the treatment of ocular symptoms in patients with primary Sjögren's syndrome (SS). METHODS A 12 week, single centre, randomised controlled study was performed. Twenty nine patients were randomly assigned to receive oral

The pivotal role of glycogen synthase kinase 3 (GSK-3) in vomiting evoked by specific emetogens in the least shrew (Cryptotis parva).

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Glycogen synthase kinase 3 (GSK-3) is a constitutively active multifunctional serine-threonine kinase which is involved in diverse physiological processes. GSK-3 has been implicated in a wide range of diseases including neurodegeneration, inflammation, diabetes and cancer. GSK-3 is a downstream

Ultra-low doses of the transient receptor potential vanilloid 1 agonist, resiniferatoxin, prevents vomiting evoked by diverse emetogens in the least shrew (Cryptotis parva).

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Published studies have shown that the transient receptor potential vanilloid 1 (TRPV1) receptor agonist, resiniferatoxin (RTX), has pro and antiemetic effects. RTX can suppress vomiting evoked by a variety of nonselective emetogens such as copper sulfate and cisplatin in several vomit-competent

Effect of oral pilocarpine on post-irradiation xerostomia in head and neck cancer patients: a single-center, single-blind clinical trial.

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OBJECTIVE The authors determined the efficacy and safety of oral pilocarpine tablet in symptomatic relief of post-radiation xerostomia in head and neck cancer patients. METHODS Thirty-three radiation-induced xerostomia patients were enrolled in a single-blind method to receive placebo 1-tablet three

Sialadenosis in bulimia. A new treatment.

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OBJECTIVE To see whether a cholinomimetic medication would help resolve the parotid gland enlargement associated with self-induced vomiting in bulimic patients. METHODS The medication was administered on an inpatient eating disorder unit to bulimic patients with refractory

Congenital Mydriasis: Diagnostic Challenge in a Case with Accompanying Neurologic Symptoms.

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A 34-year-old woman was hospitalised with acute onset nausea, vomiting, ataxia, nystagmus, blurred vision, and bilateral mydriasis. Toxicologic investigations and serologic tests for infectious aetiologies were negative. Demyelinating disease was suspected based on magnetic resonance imaging (MRI)

Broad-spectrum antiemetic efficacy of the L-type calcium channel blocker amlodipine in the least shrew (Cryptotis parva).

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The dihydropyridine l-type calcium (Ca(2+)) channel blockers nifedipine and amlodipine reduce extracellular Ca(2+) entry into cells. They are widely used for the treatment of hypertensive disorders. We have recently demonstrated that extracellular Ca(2+) entry via l-type Ca(2+) channels is involved

Painful parotid hypertrophy with bulimia: a report of medical management.

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In eating disorders, such as bulimia nervosa, body image disturbance often extends beyond the realm of weight and shape into the dermatologic spectrum. While commonly associated conditions due to binging and self-induced vomiting include cutaneous entities (e.g., Russell's sign, acne, alopecia and

[Simultaneous botulism in two brothers addicted to cocaine].

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BACKGROUND Botulism is currently an uncommon disease in which the botulinum toxin causes a progressive muscular paralysis that can lead to the death due to a failure of respiratory muscles. METHODS Two brothers, both addicted to cocaine, came to the casualty department because of a decrease of near

Accidental mydriasis from blue nightshade "lipstick".

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A 7-year-old girl presented with bilaterally dilated pupils, nausea, and vomiting 2 days after head trauma. Pilocarpine pupil testing led to the correct diagnosis of pharmacologic pupillary dilation from an unexpected and unusual source of plant poisoning, Solanum dulcamara (blue nightshade). In

A Convergence of Ophthalmic and Life-threatening Emergencies: Acute Angle Closure Glaucoma and Subarachnoid Hemorrhage.

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To report a unique case of acute angle closure glaucoma in the setting of a subarachnoid hemorrhage due to a ruptured cerebral aneurysm.Observational case report and review of the literature.A 75-year-old woman presented with

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