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Cannabinoids stimulate prostaglandin production by human gestational tissues through a tissue- and CB1-receptor-specific mechanism.
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Endocannabinoids have been implicated in the mechanisms of implantation, maintenance of pregnancy, and parturition in women. Intrauterine prostaglandin production and actions are also critical in each of these mechanisms. Hence, we have evaluated the effects of cannabinoids on prostaglandin
Cannabis Abuse or Dependence During Pregnancy: A Population-Based Cohort Study on 12 Million Births.
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OBJECTIVE
Cannabis is the most commonly used recreational drug during pregnancy in the United States. This study aimed to describe the rate of cannabis dependence or abuse use during pregnancy and its effect on obstetrical and neonatal outcomes.
METHODS
A retrospective population-based cohort of
Subarachnoid hemorrhage from a thoracic radicular artery pseudoaneurysm after methamphetamine and synthetic cannabinoid abuse: case report.
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Background Context Isolated spinal artery aneurysms not associated with vascular malformations are exceedingly rare. Purpose To present a rare case of subarachnoid hemorrhage after thoracic radiculomedullary artery pseudoaneurysm rupture in a patient who abused synthetic cannabinoids and
Cannabis-associated myocardial infarction in a young man with normal coronary arteries.
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BACKGROUND
The use of cannabis is not usually regarded as a risk factor for acute coronary syndrome. However, several cases of myocardial infarction (MI) associated with cannabis use have been reported in the scientific literature. The etiology of this phenomenon is not known.
OBJECTIVE
To present a
Ventricular fibrillation triggered by marijuana use in a patient with ischemic cardiomyopathy: a case report.
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BACKGROUND
A 60-year-old man presented to the emergency department with a left eye orbital rupture sustained during a fall due to syncope shortly after smoking more than his usual amount of marijuana.
METHODS
The patient reported experiencing a shock from his implantable cardioverter-defibrillator
Pneumomediastinum in heroin and marijuana users.
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During the past three years, more than 500 patients were seen with mediastinal or cervical emphysema or both the Ben Taub General Hospital Emergency Center. In all but 15 there was a history of recent trauma or antecedent respiratory conditions with repeated sustained intrabronchial pressure, such
Inflammatory Regulation by Driving Microglial M2 Polarization: Neuroprotective Effects of Cannabinoid Receptor-2 Activation in Intracerebral Hemorrhage.
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The cannabinoid receptor-2 (CB2R) was initially thought to be the "peripheral cannabinoid receptor." Recent studies, however, have documented CB2R expression in the brain in both glial and neuronal cells, and increasing evidence suggests an important role for CB2R in the central nervous system
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