scoulerine/corydalis

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[Isolation of alkaloids from Corydalis saxicola by high-speed counter-current chromatography].

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OBJECTIVE To develop a method for the rapid isolation of alkaloids from the crude extract of Corydalis saxicola. METHODS High-speed counter-current chromatography (HSCCC) was applied for the separation of alkaloids from Corydalis saxicola, with the biphase solvent systems comprised n-butanol-ethyl

Antiplasmodial agents from the Bhutanese medicinal plant Corydalis calliantha.

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The alkaloidal components of the Bhutanese medicinal plant Corydalis calliantha Long, which is used for the treatment of malaria, have been assessed. Four known alkaloids, protopine (1), scoulerine (2), cheilanthifoline (3) and stylopine (4) are reported from this plant for the first time. The

Positive cooperation of protoberberine type 2 alkaloids from Corydalis cava on the GABA(A) binding site.

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Protoberberine alkaloids from the rhizomes of Corydalis cava were investigated with regard to their influence on the GABA A receptor using radioreceptor assays. Whereas the protoberberine type 2 alkaloids, isoapocavidine, corydaline, tetrahydropalmatine, scoulerine and isocorypalmine, increased the

Simultaneous determination of eight bioactive alkaloids in Corydalis saxicola by high-performance liquid chromatography coupled with diode array detection.

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Corydalis saxicola Bunting (Papaveraceae), a traditional folk medicine, has been used to treat hepatic diseases for a long time. Owing to its signicant clinical effectiveness against hepatitis, cirrhosis and hepatoma, C. saxicola and its preparation are widely applied. In this study, eight

A medicinal plant compound, capnoidine, prevents the onset of inflammation in a mouse model of colitis.

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BACKGROUND The traditional uses of Corydalis dubia, Ajania nubigena and Pleurospermum amabile in the Bhutanese traditional medicine for treating disorders related to inflammatory conditions and the in vitro anti-inflammatory activity of their crude extracts inspired the isolation and the

Chemical Study of Alkaloids from Corydalis bungeana.

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From the herbs of CORYDALIS BUNGEANA, 16 alkaloids were isolated; 3 of them were identical with acetylcorynoline ( 2), corynoline ( 5), protopine ( 9), which had been obtained before from this plant. A further 11 known alkaloids: dihydrosanguinarine ( 1), acetylisocorynoline ( 3), 11-epicorynoline (

Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia.

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BACKGROUND Corydalis dubia is used in Bhutanese traditional medicine as a febrifuge and for treating infections in the blood, liver and bile which correlate to the signs and symptoms of malarial and microbial infections. OBJECTIVE To validate the ethnopharmacological uses of the plant and to

DNA topoisomerase I inhibitory alkaloids from Corydalis saxicola.

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Chemical studies of the Chinese herb Corydalis saxicola Bunting led to the isolation and identification of 14 alkaloids, 1-14. Seven of these compounds, 4-9 and 11, were obtained from this plant for the first time. Feruloylagmatine (7) is the first guanidine-type alkaloid to be identified in the

A new tetrahydroprotoberberine N-oxide alkaloid and anti-platelet aggregation constituents of Corydalis tashiroi.

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A new tetrahydroprotoberberine N-oxide alkaloid, (-)-cis-isocorypalmine N-oxide (1), together with two known compounds, 6-methoxydihydrosanguinarine (2) and norjuziphine (3), were isolated in continuing studies of the entire Formosan Corydalis tashiroi plant. The structures of these three compounds

Chemical Study on the Alkaloids of Corydalis hsuchowensis.

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Ten alkaloids were isolated from the bulb of CORYDALIS HSUCHOWENSIS W. Y. Lian nov. ined. Among them nine alkaloids are known, identified as (-)-stylopine ( 1), cheilanthifoline ( 2), (+)-adlumidine ( 3), (+)-bicuculline ( 4), sibiricine ( 5), humosine A ( 6), (+)-bulbocapnine ( 7), (-)-scoulerine (

New tetrahydroprotoberberine N-oxide alkaloids and cytotoxic constituents of Corydalis tashiroi.

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Three new tetrahydroprotoberberine N-oxide alkaloids, (-)- cis-corydalmine N-oxide, (-)- trans-corydalmine N-oxide, and (-)- trans-isocorypalmine N-oxide, along with three known benzo[ C]phenanthridine alkaloids, norsanguinarine, dihydrosanguinarine, and oxysanguinarine, six known berberine

Defined Small Molecules Produced by Himalayan Medicinal Plants Display Immunomodulatory Properties.

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Plant-derived compounds that modulate the immune responses are emerging as frontline treatment agents for cancer, infectious diseases and autoimmunity. Herein we have isolated 40 phytochemicals from five Bhutanese Sowa Rigpa medicinal plants-Aconitum laciniatum, Ajania nubegina, Corydalis crispa,

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