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Bladzijde 1 van 16 resultaten
Methods for treating sepsis using chimeric and humanized anti-histone antibodies
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SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size.
FIELD OF THE
Prodrug salts
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TECHNICAL FIELD
Provided are novel prodrug salts of selective aquaporin inhibitors, e.g., of aquaporin-4 and/or aquaporin-2, of Formula I as described below, their use as pharmaceuticals and pharmaceutical compositions comprising them, and novel intermediates used in and novel processes for their
Prodrug salts
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TECHNICAL FIELD
Provided are novel prodrug salts of selective aquaporin inhibitors, e.g., of aquaporin-4 and/or aquaporin-2, of Formula I as described below, their use as pharmaceuticals and pharmaceutical compositions comprising them, and novel intermediates used in and novel processes for their
Non-invasive intravascular volume index monitor
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BACKGROUND
Generally described, heart failure is the inability of the heart to supply sufficient blood flow to meet the body's needs. Heart failure can significantly reduce the quality of life of a patient and lead to death. Generally, heart failure is the result of the weakening or hardening of one
Non-invasive intravascular volume index monitor
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BACKGROUND
Generally described, heart failure is the inability of the heart to supply sufficient blood flow to meet the body's needs. Heart failure can significantly reduce the quality of life of a patient and lead to death. Generally, heart failure is the result of the weakening or hardening of one
Peptides as active agents to stabilize biological barriers
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The present application is a national phase application under 35 U.S.C. .sctn.371 of International Application No. PCT/EP2011/060105 filed Jun. 17, 2011, which claims priority to Austrian Patent Application No. A1010/2010 filed Jun. 18, 2010, the entire text and figures of which disclosures are
Chimeric and humanized anti-histone antibodies
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SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size.
FIELD OF THE
Chimeric and humanized anti-histone antibodies
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FIELD OF THE INVENTION
The invention relates to compositions and methods of use of anti-histone antibodies or antigen-binding fragments thereof. In particular embodiments, the antibodies bind to human histones H2B, H3 or H4. The anti-histone antibodies are of use for diagnosis and/or therapy of a
Nucleic acids encoding chimeric and humanized anti-histone antibodies
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SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size.
FIELD OF THE
Methods for treating thrombosis using chimeric and humanized anti-histone antibodies
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SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size.
FIELD OF THE
Methods for treating ischemic stroke using chimeric and humanized anti-histone antibodies
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SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size.
FIELD OF THE
Methods of treating rapidly progressive glomerulonephritis using chimeric and humanized anti-histone H4 antibodies
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SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1 SL.txt and is 71,342 bytes in size.
FIELD OF THE
Therapeutic application of Kazal-type serine protease inhibitors
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This is a national stage entry of PCT/EP2008/001009, filed Feb. 11, 2008, which claims priority to EP 07002903.8, filed Feb. 12, 2007, all of which are incorporated herein by reference.
The subject of the present invention is, in the most general aspect, the therapeutic application of the Kazal-type
PTEN inhibitor or Maxi-K channels opener
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TECHNICAL FIELD
The present invention relates to a new PTEN inhibitor or a new Maxi-K channels opener. More particularly, it relates to a PTEN inhibitor or new Maxi-K channels opener, which comprises as an active ingredient a tetrazolylalkoxy-dihydrocarbostyril compound of the formula
PTEN inhibitor or Maxi-K channels opener
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TECHNICAL FIELD
The present invention relates to a new PTEN inhibitor or a new Maxi-K channels opener. More particularly, it relates to a PTEN inhibitor or new Maxi-K channels opener, which comprises as an active ingredient a tetrazolylalkoxy-dihydrocarbostyril compound of the formula
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