stomach diseases/carbohydrate

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[Risk of chronic stomach diseases and cancer in occupational exposure to monocyclic aromatic carbohydrates (benzol and its homologs)].

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A statistically significant rise in the frequency of chronic atrophic gastritis, a precursor of cancer, has been identified in subjects exposed to monocyclic aromatic carbohydrates.

[Proteolytic activity and the carbohydrate-protein composition of gastric juice in stomach diseases].

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Carbohydrate-dependent defense mechanisms against Helicobacter pylori infection.

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Helicobacter pylori is a Gram-negative bacterium that infects over 50% of the world's population. This organism causes various gastric diseases such as chronic gastritis, peptic ulcer, and gastric cancer. H. pylori possesses lipopolysaccharide, which shares structural similarity to Lewis blood group

[Assay of serum carbohydrate antigen (CA) 19-9 in the diagnosis of gastric cancer].

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The levels of the serum carbohydrate antigen (CA) 19-9 were assayed in 284 cases including 77 patients with gastric cancer. The CA 19-9 levels were positive in 38% of gastric cancer cases, and they were significantly higher than those of benign gastric diseases. Extremely increased levels were found

Novel binding epitope for Helicobacter pylori found in neolacto carbohydrate chains: structure and cross-binding properties.

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Helicobacter pylori is a bacterium that colonizes the stomach of a majority of the global human population causing common gastric diseases like ulcers and cancer. It has an unusually complex pattern of binding to various host glycoconjugates including interaction with sialylated, sulfated, and

Clinical significance in combined detection of serum pepsinogen I, pepsinogen II and carbohydrate antigen 242 in gastric cancer.

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OBJECTIVE To explore the diagnosis value and clinical significance of combined detection of serum pepsinogen I (PG I), pepsinogen II (PG II), PG I/II and CA242 in patients with stomach diseases. METHODS Serum PG I, PG II and CA242 were detected with time-resolved fluoroimmunoassay (TRFIA) method.

Role of mucin Lewis status in resistance to Helicobacter pylori infection in pediatric patients.

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BACKGROUND Helicobacter pylori causes gastritis, peptic ulcer and is a risk factor for adenocarcinoma and lymphoma of the stomach. Gastric mucins, carrying highly diverse carbohydrate structures, present functional binding sites for H. pylori and may play a role in pathogenesis. However, little

Increased Progastrin-Releasing Peptide Expression is Associated with Progression in Gastric Cancer Patients.

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The purpose of this study was to assess the diagnostic and prognostic value of serum progastrin-releasing peptide (ProGRP) in patients with gastric cancer (GC).A total of 150 patients with GC (89 males and 61 females) were recruited, including those with

MAb L9E10 to blood group H2 antigen binds to colon cancer stem cells and inhibits tumor cell migration and invasion.

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The functions of the precursor H antigen for ABO blood group antigens are still not fully understood, particularly in cancer cells. In this study, we used hybridoma technology and NSY human colon cancer cells as an immunogen to generate a monoclonal antibody designated as MAb L9E10. The binding

Potential role of metabolomics in diagnosis and surveillance of gastric cancer.

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Gastric cancer is one of the deadliest cancers worldwide, and is especially prevalent in Asian countries. With such high morbidity and mortality, early diagnosis is essential to achieving curative intent treatment and long term survival. Metabolomics is a new field of study that analyzes metabolites

Glycosulfatase activity of H. pylori toward human gastric mucin: effect of sucralfate.

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Colonization of gastric mucosa by Helicobacter pylori, a bacterium implicated in the etiology of gastric disease, involves the cell surface sulfated glycosphingolipid receptors for the attachment. Evidence has also been obtained recently that sulfated mucus glycoproteins have the ability to

Glycosulfatase activity of Helicobacter pylori towards gastric sulfomucin: effect of nitecapone.

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A glycosulfatase activity towards human gastric sulfomucin was identified in the extracellular material elaborated by H. pylori, a pathogen implicated in the etiology of gastric disease. The purified enzyme exhibited maximum activity at pH 5.7 in the presence of 0.3% Triton X-100 and 100mM CaCl2,

The Effects of Sulglycotide on the Adhesion and the Inflammation of Helicobacter Pylori.

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Helicobacter pylori (H. pylori) is a primary etiologic factor in gastric diseases. Sulglycotide is a glycopeptide derived from pig duodenal mucin. Esterification of its carbohydrate chains with sulfate groups creates a potent gastroprotective agent used to treat various gastric

Correlation between serum CA724 and gastric cancer: multiple analyses based on Chinese population.

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Serum tumor biomarker carbohydrate antigen 724 (CA724) is noticeable for gastric cancer. Correlation between CA724 and gastric cancer was investigated based on Chinese population. Chinese Biomedical Database, Chinese Journal Full-text Database and PubMed were searched. Gastric cancer patients were

Roles of gastric mucin-type O-glycans in the pathogenesis of Helicobacter pylori infection.

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Helicobacter pylori is a Gram-negative bacterium that infects over 50% of the world's population. This organism causes various gastric diseases such as chronic gastritis, peptic ulcer, and gastric cancer. H. pylori possesses lipopolysaccharides that share structural similarity to Lewis blood group

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