Frozen or FFPE tumoral specimens suitable for DNA and RNA extraction.

Ovarian Cancer

DNA and RNA extraction from FFPE or frozen tissue sample

Institut Bergonié

MOLecular Characterization and Treatment of THYroid Carcinoma on Struma Ovarii

Description of the previous treatment for the TCSO (first treatment and relapse) in the retrospective cohort

Evaluation of the time to relapse, the progression free survival (if relapse) and the overall survivall

Research of expression of AKT1, BRAF, CTNNB1, FGFR3, HRAS, KRAS, NRAS, KIT or RET in the TCSO tissu samples

Assessed by FISH in the TCSO tissue samples

Assessed by Sanger sequencing in the TCSO tissue samples

stereotactic brain surgery of human stem cells (OK99)

Idiopathic Parkinson Disease

MRI-guided stereotactic intraputaminal cell implantation into PD patients was performed.
For target locations, measurements were made using CT-scan images fused with previous MR images. Bilateral parasagittal incisions and corresponding 14 mm burr holes were made in preparation for cell suspension injections.
To ensure complete cell suspension delivery, injections were carried out slowly for 2 min with reciprocal withdrawal of the delivery needle to avoid both damage to stem cells and brain tissue, as well as to avert reflux or bubble formation.
After surgery, patients were kept in a conventional post-operative care unit for 1 h. The day following surgery, MR images were obtained to confirm correct placement of cell suspensions. All patients were discharged 24 h after surgery.

Human Stem Cells

Procurement was performed according to NIH Guidelines

teratoma/tyrosine

MOLecular Characterization and Treatment of THYroid Carcinoma on Struma Ovarii

Parkinsonian Brain Repair Using Human Stem Cells

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