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viburnum suspensum/kanker
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Bladzijde 1 van 28 resultaten
Network pharmacology uncovers anti-cancer activity of vibsane-type diterpenes from Viburnum odoratissimum.
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Vibsane-type diterpenes, the characteristic compounds of Viburnum odoratissimum, exhibited significant cytotoxicity in many cancer cells. To search for the potential target of vibsane-type diterpenes on lung cancer, we combined methods of network pharmacology prediction and experimental
Induction of Apoptosis in Lung Cancer Cells by Viburnum grandiflorum via Mitochondrial Pathway.
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BACKGROUND Lung cancer is one of the leading causes of mortality and morbidity. Viburnum grandiflorum is a medicinal herb known for its wide spectrum of pharmacological activities, but its anti-cancer properties against lung cancer cells have not been previously investigated. The present study
The effects of gilaburu (Viburnum opulus) juice on experimentally induced Ehrlich ascites tumor in mice.
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UNASSIGNED
The aim of study was to investigate anticancer effect of Viburnum opulus (VO) on Ehrlich ascites carcinoma (EAC) bearing mice that treated with different concentrations of VO.
UNASSIGNED
For tumor transplantation; mice were inoculated with 1 × 106 EAC cells intraperitoneally and than
Influence of gilaburu (Viburnum opulus) juice on 1,2-dimethylhydrazine (DMH)-induced colon cancer.
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In this study, the effects of gilaburu (Viburnum opulus) juice on colon tumorogenesis were investigated. Eight weeks old Balb-C male mice received subcutaneous injections of 1,2-dimethylhydrazine (DMH) (20 mg/kg body weight) once a week for 12 weeks. Both the sham control (group 1) and the DMH
Compounds from Viburnum sargentii Koehne and evaluation of their cytotoxic effects on human cancer cell lines.
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Compounds were isolated from a methanol extract of the dried stem barks of Viburnum sargentii Koehne. The structures of the compounds, namely 9'-O-methylvibsanol (3), furcatoside A (4) and lareciresinol (5) were elucidated by analysis of spectroscopic data and comparison with values for previously
New diterpenoids from Viburnum awabuki.
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Eight new vibsane-type diterpenoids, vibsanins P-W (1-8), were isolated from the methanol extracts of the leaves and twigs of Viburnum awabuki. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
Cytotoxic lignans from Viburnum foetidum.
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Two new lignans, 3,4,4'-trihydroxy-3',9-dimethoxy-9,9'-epoxylignan (1), 3,4'-dihydroxy-3',4, 9-trimethoxy-9,9'-epoxylignan (2), together with one known compound, 4,4'-dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan (3), were isolated from the 95 % EtOH extract of Viburnum foetidum. The structures of
Cytotoxic iridoid aldehydes from Taiwanese Viburnum luzonicum.
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Four new iridoid aldehydes bearing (E)- or (Z)-p-coumaroyl group, luzonial A (1), luzonial B (2), luzonidial A (3), and luzonidial B (4), were isolated from a methanol extract of the dried leaves of Viburnum luzonicum collected in Kaoshiung, Taiwan and their structures were elucidated by analysis of
Sterols, triterpenes and biflavonoids of Viburnum jucundum and cytotoxic activity of ursolic acid.
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The triterpenes ursolic acid (1), 27-p-Z-coumaroyloxyursolic acid (2), 27-p-E-coumaroyloxyursolic acid, alpha-amyrine-3-palmitate and lupeol-3-palmitate were isolated through a bioactivity-guided fractionation from the acetonic extract of the aerial parts of Viburnum jucundum Morton in addition to
Cytotoxic nor-dammarane triterpenes from Viburnum hainanense Merr. et Chun.
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Five new nor-dammarane triterpenes, 12β-O-acetyl-17β-hydoxy-3,15-dioxo-20,21,22,23,24,25,26,27-octanordammanran (1), 12β-hydoxy-17β-methoxy-3,15-dioxo-20,21,22,23,24,25,26,27-octanordammanran (2), 12β-O-acetyl-3,15-dioxo-17-en-20,21,22,23,24,25,26,27-octanordammanran (3),
Iridoid glucosides and p-coumaroyl iridoids from Viburnum luzonicum and their cytotoxicity.
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Four new iridoids glucosides (1-4) and seven new iridoid aglycons (5-11) bearing (E)- or (Z)-p-coumaroyl groups were isolated from a methanol extract of the dried leaves of Viburnum luzonicum collected in Kaoshiung, Taiwan. The structures of the new compounds, named luzonoside A (1), luzonoside B
[Study on the effect of vibsane-type diterpenoids of Viburnum odoratissimum on human HepG2 cell growth and its underlying mechanism].
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OBJECTIVE
To study the antiproliferation effect on HepG2 cells and its underlying mechanism of the active chemical composition of the Viburnum Odoratissimum.
METHODS
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) reduction assay and trypan blue dye exclusion assay were used to
Cytotoxic dammarane-type triterpenoids from the leaves of Viburnum sambucinum.
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Four new dammarane-type triterpenoids (1-4) and twelve known compounds (5-16) were isolated from the leaves of Viburnum sambucinum Reinw. ex Blume. Their structures were determined by spectral data analysis, including MS and 2D NMR. Cytotoxic activity evaluation in vitro against four cancer cell
Cytotoxic and radical scavenging nor-dammarane triterpenoids from Viburnum mongolicum.
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The ethanol extract of the whole plants of Viburnum mongolicum afforded six new nor-dammarane triterpenoids: 3β,12β-dihydroxy-25,26,27-trinordammara-22-en -24,20-olide (1), 3β,12β-dihydroxy-24α-methoxy-25,26,27-trinordammara-20,24-epoxy (2),
Viburnum nervosum Leaf Extract Mediated Green Synthesis of Silver Nanoparticles: A Viable Approach to Increase the Efficacy of Anticancer Drug
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Background: There is an urgent need to devise improved alternatives for the efficient delivery of drugs to develop improved therapeutic interventions against cancers. Nanotechnology based drug delivery vehicles are in-use with obvious
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