xerostomia/diarree

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A wonderful life or diarrhea and dry mouth? Policy issues of direct-to-consumer drug advertising on television.

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Over $4 billion is being spent on direct-to-consumer advertising (DTCA) of prescription drugs. Although the greatest proportion of this media budget is spent on television, relatively few studies have investigated the key issues of DTCA on television (DTCA-TV), including fair balance, FDA

Oral rehydration therapy plus loperamide versus loperamide alone in the treatment of traveler's diarrhea.

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Eighty United States students in Mexico received either loperamide (an initial dose of 4 mg, followed by 2 mg after passage of each unformed stool, up to 8 mg/d; 40 patients) or loperamide (at the same dosage schedule) plus an oral rehydration therapy (ORT) preparation (500 mL initially, followed by

Evaluation of an enkephalin analog in men with castor oil-induced diarrhea.

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This study was a parallel, double-blind, placebo-controlled evaluation of acute doses of nifalatide, an enkephalin analog, in subjects with castor oil-induced diarrhea. Seventy-two subjects completed the study. The time to first stool after castor oil administration was significantly greater after

Family practitioner's guide to patient self-treatment of acute diarrhea.

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The majority of cases of acute, nonspecific diarrhea are of short duration, can be treated symptomatically with nonprescription medications and adequate hydration, and do not require a visit to the physician's office. If the family practitioner can determine via telephone that the patient, or the

Tianeptine vs amitriptyline for the treatment of irritable bowel syndrome with diarrhea: a multicenter, open-label, non-inferiority, randomized controlled study.

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BACKGROUND Tricyclic antidepressants have good efficacy in irritable bowel syndrome with diarrhea (IBS-D), but their clinical use is limited by considerations of tolerability. Tianeptine, another antidepressant, acts as a selective serotonin reuptake enhancer. We compared tianeptine with

[Open, multicenter, phase Ⅳ clinical trial of Shenbei Guchang capsules in treatment of diarrhea type irritable bowel syndrome].

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To evaluate the safety and effectiveness of Shenbei Guchang capsules in treatment of diarrhea type irritable bowel syndrome (yang deficiency of spleen and kidney) under widely used conditions, an open, multicenter, controlled, phase Ⅳ clinical trial was conducted in the drug clinical trial centers

Treatment of xerostomia in patients with primary Sjögren's syndrome with sulfarlem.

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Stimulated by a recent report on the favorable effect of Anetholtritione (Sulfarlem S 25) on symptoms and salivary flow rate in patients with Sjögren's Syndrome (SS), we examined the effect of Sulfarlem in an open study on 16 patients characterized by severe xerostomia. Fourteen had primary SS and

A randomized, controlled exploratory study of clonidine in diarrhea-predominant irritable bowel syndrome.

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OBJECTIVE The aim of this study was to evaluate the efficacy and tolerability of the alpha-2 adrenoreceptor agonist, clonidine, in patients with diarrhea-predominant irritable bowel syndrome (D-IBS) in a double-blind, randomized, parallel-group, placebo-controlled trial. METHODS A 2-week run-in

Acute watery diarrhea as the initial presenting feature of a pheochromocytoma in an 84-year-old female patient.

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We report the case of an 84-year-old woman who was initially admitted to the emergency room of our institution for frank dehydration caused by acute and severe secretory diarrheas along with acidosis and hypokalemia. After extensive gastrointestinal investigations, the etiology of the diarrhea

Open-label, long-term safety study of cevimeline in the treatment of postirradiation xerostomia.

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OBJECTIVE To assess the safety of long-term cevimeline treatment of radiation-induced xerostomia in patients with head-and-neck cancer; and to assess the efficacy of cevimeline in these patients. METHODS A total of 255 adults with head-and-neck cancer who had received more than 40 Gy of radiation 4

Three months of regular gum chewing neither alleviates xerostomia nor reduces overhydration in chronic hemodialysis patients.

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OBJECTIVE Gum chewing has been known to be a part of adjunctive medical therapy for cancer-related xerostomia. Nonadherence to fluid restriction in hemodialysis (HD) patients brought about by unrestricted thirst and xerostomia leads to excessive interdialytic weight gain (IWG). The effectiveness of

An open-label multicenter study to assess the safety of dextromethorphan/quinidine in patients with pseudobulbar affect associated with a range of underlying neurological conditions.

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BACKGROUND Pseudobulbar affect (PBA) is associated with neurological disorders or injury affecting the brain, and characterized by frequent, uncontrollable episodes of crying and/or laughing that are exaggerated or unrelated to the patient's emotional state. Clinical trials establishing

Development of a symptoms questionnaire for complex regional pain syndrome and potentially related illnesses: the Trauma Related Neuronal Dysfunction Symptoms Inventory.

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OBJECTIVE To develop a questionnaire to evaluate symptoms of complex regional pain syndrome type I (CRPS-I), fibromyalgia, and repetitive strain injury to determine the test-retest reliability and investigate concurrence in the clinical manifestations of CRPS-I and fibromyalgia. METHODS The Trauma

Safety and tolerability of extended-release oxybutynin once daily in urinary incontinence: combined results from two phase 4 controlled clinical trials.

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Early studies of extended-release oxybutynin in patients with overactive bladder used adjusted-dose regimens ranging from 5 to 30 mg/day to achieve an optimal balance of efficacy and tolerability. The safety and tolerability of extended-release oxybutynin at a fixed dose of 10 mg once daily

Association of oral manifestations in ulcerative colitis: A pilot study.

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UNASSIGNED Ulcerative colitis (UC) is a chronic tissue destructive inflammatory bowel disease (IBD) of autoimmune origin characterized by predominant bowel symptoms such as abdominal pain, diarrhea and relapsing and remitting rectal bleeding, leading to loss of weight. Extraintestinal

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