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Rechargeable Neurostimulators in Deep Brain Stimulation for Psychiatric Disorders
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BACKGROUND
Obsessive‐Compulsive Disorder [OCD] is a psychiatric disorder with a lifetime prevalence of 2% which is mainly characterized by obsessional ideas and compulsive behaviours and rituals. Many patients show improvement under cognitive behavioural and/or pharmacological treatment. A minority
A Comparison Study Between Ketamine Versus Tramadol for Pain Management After Major Upper Abdominal Surgery
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This is a single blind, prospective, randomized controlled trial. Forty two adults patients of American Society of Anesthesiologists (ASA) physical status I-II, aged 18-70yr, scheduled for elective upper abdominal surgery under general anaesthesia are recruited. Signed informed consent is obtained
Metoclopramide as Treatment of Clozapine-induced Hypersalivation
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Hypersalivation (sialorrhea or ptyalism) is known as a frequent, disturbing, uncomfortable adverse effect of clozapine therapy that may persist for several years. This side effect is usually dose-related. It may occur all over the day, but it is most pronounced during night sleep, since swallowing
Intranasal Fentanyl as an Analgesic for Cystoscopic Procedures
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In this double-blind study, a nasal spray of either the drug (fentanyl -- an opioid analgesic) or placebo (normal saline) is administered before the procedure. There is a 50% chance that patients receive the drug or the placebo. In either case, local Lidocaine jelly is used as an anesthetic in the
Gabapentin for Prophylaxis Intrathecal Morphine-Induced Pruritus
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The study was approved by the ethic committee of Songklanagarind Hospital in Songkhla, Thailand, and was designed as a randomized, double-blind, placebo-controlled trial. All patients gave their informed consent after receiving written information of the study. Orthopedic patients were invited to
Nicotinic Receptor Augmentation of SSRI Antidepressants
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Mecamylamine for the Treatment of Depression in SSRI-Treated Partial Responders
A. Purpose
1. To compare the nicotinic receptor antagonist mecamylamine (MEC) to placebo for the treatment of depressive symptoms in nicotine-dependent, cigarette smokers and in non-smokers who are maintained on, and are
A Study of Sertraline to Prevent PTSD
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RESEARCH DESIGN AND METHODS
1. SPECIFIC AIM 1: To assess the efficacy of sertraline in preventing posttraumatic stress disorder in children aged 6-20 after a burn, injury or reconstructive surgery following a burn injury.
2. SPECIFIC AIM 2: To assess the efficacy of sertraline in preventing
A Comparison of Bupropion SR and Placebo for Smoking Cessation
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After obtaining consent, patients will enter a two week stabilization phase followed by a 14 week treatment phase. The treatment phase begins with a 9 session group therapy led by clinic nurses trained in the educational model of the American Cancer Association. Subjects will begin the double-blind,
Quetiapine Treatment for Symptoms Associated With Borderline Personality Disorder
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Study Design: A six week, open-label, flexible dosing study using quetiapine. Subjects who qualify at Screening will then proceed to the baseline visit. If all inclusion and exclusion criteria are met, subjects will be administered quetiapine at the baseline visit. Enrollment will be 15 subjects.
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