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Side 1 fra 2272 resultater
Alanine Aminotransferase and Body Composition in Obese Men and Women.
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There is a known relationship between serum alanine aminotransferase (ALT) and obesity in humans, but the mechanism(s) are not clarified. This study investigated the associations between serum ALT and body composition in an overweight and obese population. The results are based on data from a
Influence of insulin resistance in obese patients on elevated serum alanine aminotransferase.
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OBJECTIVE
Insulin resistance has been associated with fat liver and non-alcoholic fatty liver disease. The aim of our study was to study the influence of insulin resistance in obese patients on elevated serum alanine aminotransferase.
METHODS
A population of 91 obesity non diabetic outpatients was
Relationship between insulin resistance and serum alanine aminotransferase as a surrogate of NAFLD (nonalcoholic fatty liver disease) in obese Korean children.
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There has been increasing number of obese children who accompany obesity-related comorbidities. It has been known that nonalcoholic fatty liver disease (NAFLD) as one of obesity-related comorbidities is related with insulin resistance. So, we investigated the relation between insulin resistance and
Alanine aminotransferase elevation in obese infants and children: a marker of early onset non alcoholic Fatty liver disease.
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BACKGROUND
Elevated aminotransferases serve as surrogate markers of non-alcoholic fatty liver disease, a feature commonly associated with the metabolic syndrome. Studies on the prevalence of fatty liver disease in obese children comprise small patient samples or focus on those patients with liver
Contribution of glycerol and alanine to basal hepatic glucose production in the genetically obese (fa/fa) rat.
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Increased hepatic glucose production has been reported to occur in the insulin-resistant genetically obese fa/fa rats. The possible existence of an increased basal gluconeogenesis in obese rats was investigated, upon comparing the metabolic fate of glycerol and alanine in liver of fed anaesthetized
A better parameter in predicting insulin resistance: obesity plus elevated alanine aminotransferase.
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OBJECTIVE
To investigate the association of obesity and elevated alanine aminotransferase with insulin resistance and compare these factors with metabolic syndrome.
METHODS
We enrolled a total of 1308 male workers aged from 22 to 63 years. Data was extracted from the workers' periodic health
The metabolic fate of an oral 14C-alanine load in the obese Zucker rat.
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Following an oral 14C-alanine load, obese Zucker rats showed the same rate of intestinal amino acid absorption as their lean counterparts. Alanine absorption was unchanged by a 24 h starvation period. The whole-body oxidation of the absorbed tracer was lower in the fa/fa rats and was significantly
Abdominal obesity validates the association between elevated alanine aminotransferase and newly diagnosed diabetes mellitus.
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To examine how elevated alanine aminotransferase (ALT) could be associated with newly diagnosed diabetes mellitus. We conducted a cross-sectional analysis on a mass health examination. The odds ratios (ORs) for diabetes mellitus and newly diagnosed diabetes mellitus were compared between people with
Association of Alanine Aminotransferase With Different Metabolic Phenotypes of Obesity in Children and Adolescents: The CASPIAN-V Study
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Aim: To determine the association of alanine aminotransferase with different metabolic phenotypes of obesity in a nationally- representative sample of Iranian children and adolescents. Methods: This national study was conducted in the framework of the fifth survey of a national
Changes in alanine turnover rate due to nutritional and genetic obesity in the rat.
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The changes in alanine turnover were determined in Zucker rats, which were either genetically obese (fa/fa) or rendered obese by dietary treatment (cafeteria fed). The whole body rate of alanine turnover was higher in genetically obese rats than in rats in which obesity was induced by diet
L-alanine transport in small intestine brush-border membrane vesicles of obese rats.
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Membrane vesicles from the small intestine brush border were obtained and used to determine the possible effects of genetic or nutritional obesity on L-alanine uptake. Membrane vesicles from Zucker fa/fa obese rats and cafeteria diet-fed Zucker Fa/? rats showed the same characteristics as those of
In vivo C14-L-alanine metabolism in rat dietary obesity induced by cafeteria diet.
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The "in vivo" handling of L-alanine in 24 hours starved rats, in which obesity was induced by feeding with cafeteria diet, was compared with that of starved control rats. 14C-alanine was administered in trace amounts in order not to affect the normal handling of this amino acid. The results obtained
Effect of fasting on the disappearance of injected alanine and 3-hydroxybutyrate in obese subjects.
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1. The blood concentrations of 3-hydroxybutyrate and alanine were measured before and after they were separately injected into obese patients who were taking a 1.68 MJ (400 kcal) diet and again when they had starved for 4 days and 28 days. 2. The disappearance of the injected metabolite was
Insulin and Na-dependent alanine transport in skeletal muscle of obese Zucker (fa/fa) rats.
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Obese Zucker (fa/fa) rat skeletal muscle is characterized by a reduced rate of muscle protein deposition possibly due to alterations in amino acid transport. The purpose of the present study was to investigate alanine transport in plasma membrane vesicles from skeletal muscle of lean and obese
Plasma glucagon response to intravenous alanine in obese and non-obese subjects.
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To investigate glucagon (IRG) and insulin (IRI) responses to alanine infusion in obesity and to assess the effect of body weight reduction with respect to hormonal balance, we compared six obese subjects with nine normal weight controls. None of the subjects were diabetic by OGTT criteria. Plasma
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