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analgesic/hypoxia

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Recurrent hypoxemia in children is associated with increased analgesic sensitivity to opiates.

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BACKGROUND Postsurgical administration of opiates in patients with obstructive sleep apnea (OSA) has recently been linked to an increased risk for respiratory complications. The authors have attributed this association to an effect of recurrent oxygen desaturation accompanying OSA on endogenous
Complex regional pain syndrome (CRPS) is related to microcirculation impairment caused by tissue hypoxia and peripheral cytokine overproduction in the affected human limb and chronic post-ischemic pain (CPIP) is considered as an animal model for this intractable disease. Previous
Aquatic organisms face multiple stressors in natural ecosystems. More and more often painkillers are detected in surface waters since their prescription has increased worldwide within the last years. Here we examined the effects of the non-steroidal anti-inflammatory drug (NSAID) diclofenac and

[Protective effect of eptazocine, a novel analgesic, against cerebral hypoxia-anoxia in mice].

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Cerebral protective effect of eptazocine, a mu-antagonist-kappa-agonist, was investigated using mice subjected to hypoxia-anoxia. Eptazocine (1 to 10 mg/kg) prolonged the survival time of mice subjected to KCN (3 mg/kg, i.v.) injection in a dose-dependent manner, and this effect was completely

[Protective effect of narcotic analgesics on the mother, fetus and offspring in hypoxia].

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The protective effect of the narcoanalgetics, viadril (hydroxydione sodium succinate) and administered intraperitoneally in doses of 5 and 20 mg/kg was studied in the experiment on 146 pregnant noninbred white rats with simulated hemic hypoxia in the late pregnancy (the 19th day). The aforementioned

[Change in the anodyne properties of morphine in acute hypoxic hypoxia].

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[Effectiveness of narcotic analgesics in acute hypoxic hypoxia and brain ischemia].

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[Role of oxygen deficiency in the mechanism of the pain-relieving action of narcotic analgesics].

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[The effect of hemic hypoxia on the analgesic properties of narcotic analgesics].

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[Effect of narcotic analgesics on sensitivity to hypoxia in animals].

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[Effect of hemic hypoxia on analgetic properties of narcotic analgesics].

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[Effect of opiate receptor agonists and antagonists on the resistance of animals to hypoxic hypoxia].

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The effects of morphine, a series of synthetic enkephalin analogs and antagonists of narcotic analgesics on the animals' survival rate under hypoxic hypoxia were studied in experiments on mice, rabbits, and cats. It was shown that the agonists of mu-opiate receptors, morphine, FK 33-824
The aim of the present study was to determine whether U-50,488H and U-62,066E, kappa-opioid receptor agonists cause a neuroprotective action against hypoxia/hypoglycemia-induced reduction in 2-deoxyglucose (2-DG) uptake of hippocampal slices from U-50,488H-tolerant rats. Both U-50,488H and U-62,066E
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