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The present invention relates to the field of bioorgmic chemistry and concerns N-acyl derivatives of amino acids and pharmaceutically acceptable salts thereof, novel processes for synthesis of said compounds as well as pharmaceutical compositions based on them and use thereof in medicine as
The present invention relates to the field of bioorganic chemistry and concerns N-acyl derivatives of amino acids and pharmaceutically acceptable salts thereof, novel processes for synthesis of said compounds as well as pharmaceutical compositions based on them and use thereof in medicine as
The invention relates to a novel piperazine derivative, an acid salt thereof, process and use thereof.
Indomethacin is widely used as an anti-inflammatory agent and is considered to exhibit the anti-inflammatory effect by restricting the production of prostaglandins and thromboxane by inhibiting the
BACKGROUND OF THE INVENTION
The present invention relates to certain zwitterionic bicyclic compounds and to pharmaceutical compositions and methods of use employing such compounds.
An article by Bowman et al. entitled "The Synthesis of Some Dialkylamino-2-quinolones," Journal of the Chemical
BACKGROUND OF THE INVENTION
(a) Field of the Invention
This invention relates to 1-[(3- or 4-benzoylphenyl)-lower-alkyl]-[(CH.sub.2).sub.n --N.dbd.B]-substituted-piperidines and analogs thereof, useful as anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory agents;
This Application is the National Phase Under 35 U.S.C. .sctn.371 of PCT International Application No. PCT/BR2007/000186 which has an International filing date of Jul. 19, 2007, which claims priority to Brazilian Application No. PI0602885-3 filed on Jul. 21, 2006 and Brazilian Application No.
BACKGROUND OF THE INVENTION
This invention relates to dihydropyridines, specifically to certain 4-aryl-5-carbamoyl-1,4-dihydropyridines which are useful in the treatment of allergic and inflammatory conditions in humans and animals.
A number of 1,4-dihydropyridines have been previously described as
The invention relates to novel 2-fluoroalkylated 4-acylresorcinol ethers of the formula ##STR2## in which R.sub.1 is lower alkyl, R.sub.2 is fluorinated lower alkyl, R.sub.3 is hydrogen, lower alkoxy, trifluoromethyl or halogen, alk is an alkylene or hydroxyalkylene radical which is uninterrupted or
The invention relates to novel 2-fluoroalkylated 4-acryleresorcinol ethers of the formula ##STR4## in which R.sub.1 is lower alkyl, R.sub.2 is fluorinated lower alkyl, R.sub.3 is hydrogen, lower alkoxy, trifluoromethyl or halogen, alk is an alkylene or hydroxyalkylene radial which is uninterrupted
BACKGROUND OF INVENTION
The present invention relates to substituted 2,3-dihydro-6-(hydroxy)pyrimido[2,1-f]purine-4,8(1H, 9H)-diones and tautomers thereof. These compounds are useful as anti-inflammatory agents for treating inflammatory conditions such as arthritis, spondylitis, and tendonitis in
This invention relates to new pharmaceutically active compounds and more particularly to certain new thiazines possessing useful pharmacologic activities, especially regulating the activity of lipoxygenase and as such possess therapeutic value in the treatment of inflammatory conditions and allergic
The present invention relates to pyrazolopyridines having useful pharmacological activity, to a process for their preparation and to their use as anti-inflammatories.
J. Heterocycl. Chem. 1971, 8(6), 1035-7 discloses compounds of the formula (A): ##STR2## wherein R is NH.sub.2, OH, NAc.sub.2 or Cl.
The present invention is concerned with 4-Quinolone derivatives, processes for their production, pharmaceutical compositions wherein said compounds or pharmaceutically acceptable salts thereof are the active agent and to methods of effecting anti-inflammatory, anti-allergenic, anti-tussive,
The invention relates to novel 4-acylresorcinol ethers of the formula ##STR2## in which R.sub.1 represents lower alkyl, R.sub.2 represents lower alkyl, lower alkenyl or lower alkynyl, R.sub.3 represents hydrogen, lower alkoxy, trifluoromethyl or halogen, alk represents an alkylene radical, one of
This invention relates to novel aromatic heterocyclic carboxylic acid derivatives, to processes for preparing them, to pharmaceutical compositions containing them and their use in medicine.
It is known that certain arachidonic acid metabolites can produce harmful effects in man. For example, some