Anti allergic / diarrhea

Indole-2-alkanoic acids compositions of and anti allergic use thereof

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SUMMARY OF THE INVENTION This invention relates to prostaglandin antagonists useful in treating a variety of conditions, such as allergic asthma where excessive contractile activity of prostaglandins and prostaglandin biosynthetic intermediates occur. These compounds antagonize the actions of

Heterocycle-fused morphinans, use thereof and preparation thereof

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TECHNICAL FIELD The present disclosure relates to certain heterocycle fused morphianans. Compounds of the present disclosure are mixed mu agonist delta antagonists or dual mu agonist/delta agonists or antagonists at mu, delta and kappa opioid receptors. Compounds of the present disclosure are useful

Indenyl hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase

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BACKGROUND OF THE INVENTION The leukotrienes and their biological activities, especially their role in various disease states, have been extensively studied. Their properties are described in the book Leukotrienes and Lipoxygenases, Ed., J. Rokach, Elsevier, N.Y., 1989. Inhibitors of the

Dibenzoheterocyclic hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase

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BACKGROUND OF THE INVENTION The leukotrienes and their biological activities, especially their role in various disease states, have been extensively studied. Their properties are described in the book Leukotrienes and Lipoxygenase, Ed., J. Rokach, Elsevier, N.Y., 1989. Inhibitors of the

(Quinolin-2-ylmethoxy)indole/cyclodextrin complex

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BACKGROUND OF THE INVENTION EP 419,049, Prasit et al., Mar. 27, 1991, describes a series of quinolin-2-ylmethoxy indoles useful as inhibitors of leukotriene biosynthesis. Examples 1 and 1A therein teach the synthesis of 3-[N-(p-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl]-

(Azaarylmethoxy)indoles as inhibitors of leukotriene biosynthesis

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BACKGROUND OF THE INVENTION European Patent Applications 166,591 and 275,667 disclose a series of indole-based compounds with activity as prostaglandin antagonists and inhibitors of leukotriene biosynthesis respectively. In EP 181,568 and EP 200,101 are disclosed a series of compounds, containing

(hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis

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BACKGROUND OF THE INVENTION European Patent Applications 166,591 and 275,667 disclose a series of indole-based compounds with activity as prostaglandin antagonists and inhibitors of leukotriene biosynthesis respectively. In EP 181,568 and EP 200,101 are disclosed a series of compounds, containing

Bicyclic-azaarylmethoxy) indoles as inhibitors of leukotriene biosynthesis

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BACKGROUND OF THE INVENTION European Patent Applications 166,591 and 275,667 disclose a series of indole-based compounds with activity as prostaglandin antagonists and inhibitors of leukotriene biosynthesis respectively. In EP 181,568 and EP 200,101 are disclosed a series of compounds, containing

(Bicyclic-hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis

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BACKGROUND OF THE INVENTION European Patent Applications 166,591 and 275,667 disclose a series of indole-based compounds with activity as prostaglandin antagonists and inhibitors of leukotriene biosynthesis respectively. In EP 181,568 and EP 200,101 are disclosed a series of compounds, containing

Fluorinated quinoline indoles as inhibitors of the biosynthesis of leukotrienes

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CROSS REFERENCE The compounds of Formula I' are described in U.S. Ser. No. 650,825 filed Feb. 5, 1991, which is now U.S. Pat. No. 5,204,344, and incorporated herein by reference. BACKGROUND OF THE INVENTION European Patent Applications 166,591 and 275,667 disclose a series of indole-based compounds

Amorphous (quinolin-2-ylmethoxy)indole compounds which have useful pharmaceutical utility

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BACKGROUND OF THE INVENTION EP 419,049, Prasit et al., Mar. 27, 1991, describes a series of quinolin-2-ylmethoxy indoles useful as inhibitors of leukotriene biosynthesis. Examples 1 and 1A therein teach the synthesis of 3-[N-(p-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl]-

Amorphous (quinolin-2-ylmethoxy)indole compounds useful for treating inflammatory diseases

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BACKGROUND OF THE INVENTION EP 419,049, Prasit et al., Mar. 27, 1991, describes a series of quinolin-2-ylmethoxy indoles useful as inhibitors of leukotriene biosynthesis. Examples 1 and 1A therein teach the synthesis of 3-[N-(p-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl]-

(Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes

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BACKGROUND OF THE INVENTION European Patent Applications 166,591 and 275,667 disclose a series of indole-based compounds with activity as prostaglandin antagonists and inhibitors of leukotriene biosynthesis respectively. In EP 181,568 and EP 200,101 are disclosed a series of compounds, containing

(Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes

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BACKGROUND OF THE INVENTION European Patent Applications 166,591 and 275,667 disclose a series of indole-based compounds with activity as prostaglandin antagonists and inhibitors of leukotriene biosynthesis respectively. In EP 181,568 and EP 200,101 are disclosed a series of compounds, containing

(Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes

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BACKGROUND OF THE INVENTION European Patent Applications 166,591 and 275,667 disclose a series of indole-based compounds with activity as prostaglandin antagonists and inhibitors of leukotriene biosynthesis respectively. In EP 181,568 and EP 200,101 are disclosed a series of compounds, containing

anti allergic/diarrhea

Indole-2-alkanoic acids compositions of and anti allergic use thereof

Heterocycle-fused morphinans, use thereof and preparation thereof

Indenyl hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase

Dibenzoheterocyclic hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase

(Quinolin-2-ylmethoxy)indole/cyclodextrin complex

(Azaarylmethoxy)indoles as inhibitors of leukotriene biosynthesis

(hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis

Bicyclic-azaarylmethoxy) indoles as inhibitors of leukotriene biosynthesis

(Bicyclic-hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis

Fluorinated quinoline indoles as inhibitors of the biosynthesis of leukotrienes

Amorphous (quinolin-2-ylmethoxy)indole compounds which have useful pharmaceutical utility

Amorphous (quinolin-2-ylmethoxy)indole compounds useful for treating inflammatory diseases

(Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes

(Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes

(Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes

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