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anti inflammatory/infarction
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N-acyl amino acid derivatives, a method for the preparation thereof, a pharmaceutical composition and use thereof as anti-allergic, anti-inflammatory and hypolipidemic agents
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The present invention relates to the field of bioorgmic chemistry and concerns N-acyl derivatives of amino acids and pharmaceutically acceptable salts thereof, novel processes for synthesis of said compounds as well as pharmaceutical compositions based on them and use thereof in medicine as
N-acylic aminoacid derivatives, method for the production thereof, pharmacological composition and the use in the form anti-allergic, anti-inflammatory and hypolipidemic agents
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The present invention relates to the field of bioorganic chemistry and concerns N-acyl derivatives of amino acids and pharmaceutically acceptable salts thereof, novel processes for synthesis of said compounds as well as pharmaceutical compositions based on them and use thereof in medicine as
Methods for reducing morality associated with acute myocardial infarction
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BACKGROUND
1. Technical Field
This disclosure relates to methods for reducing mortality in myocardial infarction patients. More specifically, this disclosure relates to the administration of an anti-inflammatory compound to myocardial infarction patients receiving a stent in connection with
Assessment of iron deposition post myocardial infarction as a marker of myocardial hemorrhage
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FIELD OF INVENTION
The invention is directed to methods for diagnosing reperfusion and non-reperfusion hemorrhage, predicting cardiac arrhythmias, sudden cardiac death, and adverse remodeling in subjects post myocardial infarction. The invention also provides treatment methods for subjects at
Method for counteracting blood platelet aggregation in a patient in need thereof
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The present invention relates to a method for treating an inflammatory pathological condition in a patient in need thereof, comprising administering on empty stomach an anti-inflammatory effective amount of 2-methoxyphenyl-1-methyl-5p-methylbenzoyl-pyrrol-2-acetamido acetate (known also as
Protein S protects the nervous system from injury
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BACKGROUND OF THE INVENTION
This invention relates to the use of protein S and/or variants thereof as neuroprotective agents for treating brain disorders and other pathological conditions. The ability of protein S and variants thereof to act as cell survival factors on cells of the nervous systems
Treatment for ischemic stroke
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STATEMENT AS TO FEDERALLY SPONSORED RESEARCH
Not applicable.
FIELD OF THE INVENTION
The invention relates generally to the fields of neurology, pharmaceuticals, and medicine. More particularly, the invention relates to the use of agents to protect brain tissue from ischemia/reperfusion
Treatment for ischemic stroke
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STATEMENT AS TO FEDERALLY SPONSORED RESEARCH
Not applicable.
FIELD OF THE INVENTION
The invention relates generally to the fields of neurology, pharmaceuticals, and medicine. More particularly, the invention relates to the use of agents to protect brain tissue from ischemia/reperfusion
Treatment for ischemic stroke
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STATEMENT AS TO FEDERALLY SPONSORED RESEARCH
Not applicable.
FIELD OF THE INVENTION
The invention relates generally to the fields of neurology, pharmaceuticals, and medicine. More particularly, the invention relates to the use of agents to protect brain tissue from ischemia/reperfusion
Targeting recombinant therapeutics to circulating red blood cells
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BACKGROUND OF THE INVENTION
Many pathological processes such as thrombosis and hemorrhages, systemic inflammation and cytokine shock, pathologies of transport of lipids and other biological compounds, are initiated or/and develop in the blood. Accordingly, activity of therapeutic agents for optimal
Peptides that promote lipid efflux
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FIELD OF THE INVENTION
This present invention relates to peptides or peptide analogs that contain functional domains and promote lipid efflux. These peptides or peptide analogs optionally contain one or more anti-inflammatory domain and one or more domains that affects lecithin cholesterol
Method of inhibiting oxidants using alkylaryl polyether alcohol polymers
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BACKGROUND OF THE INVENTION
The present invention relates to use of alkylaryl polyether alcohol polymers as antioxidants to suppress certain oxidant chemical reactions that cause tissue injury and disease in mammals and plants.
Oxygen is life-giving to aerobic plants and animals who depend on it for
Endothelin converting enzyme inhibitors
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TECHNICAL FIELD
The present invention relates to compounds and compositions which inhibit endothelin converting enzyme (ECE), processes for making such compounds, synthetic intermediates employed in these processes and methods for suppressing endothelin production, treating hypertension, congestive
(4-arylsulfonylamino)-tetrahydropyran-4-carboxylic acid hydroxamides
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BACKGROUND OF THE INVENTION
The present invention relates to (4-arylsulfonylamino)-tetrahydropyran-4-carboxylic acid hydroxamide derivatives, and to pharmaceutical compositions and methods of treatment.
The compounds of the present invention are inhibitors of zinc metalloendopeptidases, especially
Carbostyril derivative
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TECHNICAL FIELD
The present invention relates to a novel carbostyril derivative, a salt thereof, a process for producing said derivative, and a pharmaceutical composition for inhibiting platelet aggregation which contains said novel carbostyril derivative as an active ingredient.
BACKGROUND OF THE
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