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candidiasis/phosphatase
Koblingen er lagret på utklippstavlen
Side 1 fra 77 resultater
Association of the lymphoid protein tyrosine phosphatase, R620W variant, with chronic mucocutaneous candidiasis.
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Effect of farnesol on a mouse model of systemic candidiasis, determined by use of a DPP3 knockout mutant of Candida albicans.
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This work extends our previous observation that the fungus Candida albicans secretes micromolar levels of farnesol and that accumulation of farnesol in vitro prevents the yeast-to-mycelium conversion in a quorum-sensing manner. What does farnesol do in vivo? The purpose of this study was to
[A clinical study of chronic disseminated candidiasis in patients with acute leukemia].
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OBJECTIVE
To deepen the understanding of chronic disseminated candidiasis (CDC) in patients with acute leukemia (AL).
METHODS
CDC was investigated in 119 AL patients who received induction chemotherapy from August 2004 to May 2005. Clinical manifestations, laboratory tests, imaging modalities,
[Hepatosplenic candidiasis in acute leukaemia patients].
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BACKGROUND
Hepatosplenic candidiasis is a disseminated invasive fungal infection that may affects patients with acute leukaemia. The main clinical manifestation is a persistent fever in patients recovered from prolonged neutropenia after recent chemotherapy.
METHODS
The authors present three
Focal hepatic candidiasis: a distinct clinical variant of candidiasis in immunocompromised patients.
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Focal hepatic candidiasis is a distinct clinical variant of candidiasis in immunocompromised hosts. Although affected patients may exhibit previous evidence of extra-hepatic candidal infection, manifestations of disease at the time hepatic involvement is documented are localized to the liver. Five
Hepatosplenic candidiasis: an overlooked cause of prolonged fever during recovery from an episode of neutropenia.
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Two cases of hepatosplenic candidiasis (HSC) are reported occurring after protracted episodes of neutropenia, induced by chemotherapy for acute leukemia in one case and drug hypersensitivity in the other. The disease presented with persistent or recurrent fever after correction of the neutropenia
Hepatosplenic candidiasis in children with cancer. Three cases in leukemic children and a literature review.
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Three children with acute leukemia presented with prolonged fever and neutropenia after cytostatic therapy, which was followed by abdominal pain, hepatomegaly, and hepatic dysfunction with raised serum alkaline phosphatase. Abdominal CT scan and ultrasound demonstrated multiple small lesions
Computerized tomography in the diagnosis of systemic candidiasis in patients with acute leukemia.
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Seven patients with acute leukemia and systemic candidiasis presented with a clinical syndrome of fever, abdominal pain, organomegaly, and a cholestatic pattern of hepatic dysfunction with an elevated alkaline phosphatase and normal transaminases. The abdominal CT scan demonstrated diffuse hepatic
Fluconazole in the treatment of hepatosplenic candidiasis.
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Hepatosplenic candidiasis has increased in frequency among immunocompromised hosts. Risk factors include hematologic malignancy, intensive chemotherapy, prolonged neutropenia, and treatment with broad-spectrum antibiotics. Patients most commonly present with abdominal pain, persistent fevers despite
Hepatosplenic candidiasis in children with acute leukemia.
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Three children with acute lymphoblastic leukemia developed disseminated fungal disease predominantly involving the liver and spleen. The three patients were undergoing induction chemotherapy and had neutropenia when they presented prolonged fever not responsive to antibiotics. Once neutropenia was
Protection from systemic Candida albicans infection by inactivation of the Sts phosphatases.
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The human fungal pathogen Candida albicans causes invasive candidiasis, characterized by fatal organ failure due to disseminated fungal growth and inflammatory damage. The suppressor of TCR signaling 1 (Sts-1) and Sts-2 are two homologous phosphatases that negatively regulate signaling pathways in a
[The cellular acid phosphatase activity in yeast-like fungi of the genus Candida exposed to ultrasound, polyene antibiotics and dyes].
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The activity of one of the lysosomal membrane marker enzymes--acid phosphatase from the Candida yeast fungi on their exposure to ultrasound (US), polyenic antibiotics (amphotericin B and nystatin) dye antiseptics (ethacridine lactate, methylene blue), and their combinations was assayed. The impact
The Candida albicans phosphatase Inp51p interacts with the EH domain protein Irs4p, regulates phosphatidylinositol-4,5-bisphosphate levels and influences hyphal formation, the cell integrity pathway and virulence.
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We previously identified Candida albicans Irs4p as an epidermal growth factor substrate 15 homology (EH) domain-containing protein that is reactive with antibodies in the sera of patients with candidiasis and contributes to cell wall integrity, hyphal formation and virulence. In this study, we use a
Hepatic candidiasis in cancer patients: the evolving picture of the syndrome.
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Focal hepatosplenic candidiasis has been recognized with increasing frequency in recent years. We reviewed the cases of eight patients seen between 1982 and 1985, and information on 60 patients whose cases have been reported in the world literature. The characteristics of focal hepatosplenic
[Testing the efficacy of fluconazole in treatment of oral and throat candidiasis in patients after kidney transplantation].
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Eleven kidney transplant recipients with the oral or/and throat candidiasis which occurred during the first 3 months after transplantation were studied. Fluconazole was administered orally in the dose of 50 mg each 24, 48, 72 h, according to creatinine clearance. No clinical symptoms of candidiasis
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