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chemotherapy/hemorrhage
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Cell-derived microparticles as hemostatic agents for control of hemorrhage and treatment of bleeding disorders
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to compositions comprising membrane-derived microparticles that promote platelet adhesion, aggregation, blood clot formation and to a method for treating bleeding disorders, particularly blood coagulation disorders, platelet
Methods and compositions for the diagnosis and treatment of hematological disorders using 2777
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BACKGROUND OF THE INVENTION
Hematological disorders are blood associated disorders. Blood is a highly specialized tissue which carries oxygen and nutrients to all parts of the body and waste products back to the lungs, kidneys and liver for disposal. Thus, blood maintains communication between
Process for inhibiting platelet aggregation
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BRIEF DESCRIPTION OF THE INVENTION
This invention relates to the prevention of platelet aggregation or thrombus formation by the addition of a compound of the Formula I to the plasma surrounding the platelets.
DETAILED DESCRIPTION OF THE INVENTION
The compounds of the Formula I are old compounds
Process for inhibiting platelet aggregation
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BRIEF DESCRIPTION OF THE INVENTION
This invention relates to the prevention of platelet aggregation or thrombus formation by the addition of a compound of the Formula I to the plasma surrounding the platelets.
DETAILED DESCRIPTION OF THE INVENTION
The compounds of the Formula I are old compounds
Process of treatment
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BRIEF DESCRIPTION OF THE INVENTION
This invention relates to the prevention of platelet aggregation or thrombus formation by the addition of a compound of the Formula I to the plasma surrounding the platelets.
DETAILED DESCRIPTION OF THE INVENTION
The compounds of the Formula I are old compounds
Thrombocytopoiesis stimulating factor
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TECHNICAL FIELD
The present invention relates to a novel physiologically active substance (thrombocytopoiesis stimulating factor) having activity in acting on cells in the megakaryocyte system, in promoting their differentiation and maturation, and in promoting the formation of platelets, as well as
Acetylcholinesterase-derived peptides and uses thereof
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FIELD OF THE INVENTION
The invention is directed to the field of stem cell survival and expansion. Specifically, the invention is directed at the stem cell survival and expansion effects of peptides derived from acetylcholinesterase. In addition, the invention relates to a system for screening of
Method for increasing the activity of the immune system of a mammal at risk of inflammatory diseases
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FIELD OF THE INVENTION
The present invention relates to methods for increasing the activity of the immune system and, especially, to methods for increasing the activity of the immune system by modulation of endogenous ectophosphatase levels. According to a particularly preferred embodiment, the
Inhibition of platelet aggregation with substituted phenylhydratropic acid compounds
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BRIEF DESCRIPTION OF THE INVENTION
This invention relates to the prevention of platelet aggregation or thrombus formation by the addition of a compound of the Formula 1 to the plasma surrounding the platelets.
DETAILED DESCRIPTION
The compounds of the Formula 1 are old compounds known in the art.
Process for inhibiting platelet aggregation
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BRIEF DESCRIPTION OF THE INVENTION
This invention relates to the prevention of platelet aggregation or thrombus formation by the addition of a compound of the Formula 1 to the plasma surrounding the platelets.
DETAILED DESCRIPTION OF THE INVENTION
The compounds of the Formula 1 are old compounds
Process for treating elevated platelet adhesiveness
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BRIEF DESCRIPTION OF THE INVENTION
This invention relates to the prevention of platelet aggregation or thrombus formation by the addition of a compound of the Formula 1 to the plasma surrounding the platelets.
DETAILED DESCRIPTION OF THE INVENTION
The compounds of the Formula 1 are old compounds
Human G-protein coupled receptor
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The present invention relates to novel identified polynucleotides, polypeptides encoded by them and to the use of such polynucleotides and polypeptides, and to their production. More particularly, the polynucleotides and polypeptides of the present invention relate to a G-protein coupled receptor
Antibodies immunospecific for a novel human G-protein coupled receptor family
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The present invention relates to novel identified polynucleotides, polypeptides encoded by them and to the use of such polynucleotides and polypeptides, and to their production. More particularly, the polynucleotides and polypeptides of the present invention relate to a G-protein coupled receptor
Activated protein C variants with normal cytoprotective activity but reduced anticoagulant activity
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FIELD OF THE INVENTION
The present invention relates to variants (mutants) of recombinant protein C and activated protein C, an enzyme that normally has anti-thrombotic, anti-inflammatory, and anti-apoptotic activities. The recombinant activated protein C mutants of the invention have markedly
Activated protein C variants with normal cytoprotective activity but reduced anticoagulant activity
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FIELD OF THE INVENTION
The present invention relates to variants (mutants) of recombinant protein C and activated protein C, an enzyme that normally has anti-thrombotic, anti-inflammatory, and anti-apoptotic activities. The recombinant activated protein C mutants of the invention have markedly
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