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Clozapine is an alternative antipsychotic medication used to control symptoms of schizophrenia and to reduce risks of suicidal behavior in patients who did not adequately respond to standard medication. Due to severe side effects including cardiomyopathy and myocarditis its clinical OBJECTIVE
The objective of this study was to assess the relationships among chest pain, psychiatric disorder, and early experience of ill health.
METHODS
The Medical Research Council National Survey of Health and Development is a population-based birth cohort study established in 1946 (N = 5362).
BACKGROUND
Topiramate, an anticonvulsant used for prophylaxis of migraines and epilepsy, is commonly associated with adverse effects of cognitive dulling and fatigue. Chest pain is a potential adverse effect that to our knowledge has not been reported with the use of topiramate.
METHODS
We present
One hundred adults with a chief complaint of chronic fatigue were evaluated in an outpatient setting to determine a possible association with somatization disorder. Somatization disorder was diagnosed in 15 patients. Eight functional somatic symptoms were reported more frequently by these patients:
BACKGROUND
There is a demand for a highly sensitive and specific point-of care test to detect acute myocardial infarction (AMI). It is unclear if a high-sensitivity troponin assay will have enough discriminative power to become a decision support in primary care. The aim of this study was to
BACKGROUND Drug induced lupus erythematosus is considered an autoimmune entity which is precipitated by medications. Hydrochlorothiazide has been recognized to cause subacute cutaneous lupus erythematosus, but very few cases of systemic drug induced lupus systemic erythematosus have been reported.
Fatigue is a common and distressing but poorly understood symptom among patients with heart failure (HF). This study sought to evaluate the prevalence, predictors, and prognostic value of clinically documented fatigue in newly diagnosed HF patients from the community.
This retrospective cohort study
A 34-year-old male presented with retrosternal chest pain, fatigue, shortness of breath, and a history of a previous episode of myocarditis four years prior. He had elevated troponin T, normal skeletal muscle enzymes, and negative inflammatory markers. Cardiac magnetic resonance imaging (MRI)
OBJECTIVE
To improve our understanding and facilitate early diagnosis of pulmonary artery sarcoma (PAS).
METHODS
The clinical and radiological features of 9 histopathologically confirmed patients with PAS were retrospectively analyzed.
RESULTS
Our PAS cohort consisted of 5 males and 4 females, with
Post-cardiac injury syndrome is a form of secondary pericarditis with or without pericardial effusion, which typically occurs weeks to months following an injury to the heart or pericardium. Disease activity can be followed with serial testing of inflammatory markers e.g. C-reactive BACKGROUND
Little is known about the association of atrial fibrillation symptom burden with quality of life and outcomes.
RESULTS
In the Prevention of Thromboembolic Events-European Registry in Atrial Fibrillation (n=6196 patients with atrial fibrillation; mean±SD age, 71.8±10.4 years; 39.7% women),
Symptoms of mitral valve prolapse syndrome, the most common valvular disorder, include anxiety, fatigue, palpitations, headaches, and chest pain, to name a few. This syndrome is effectively treated in a nurse-managed, outpatient clinic that specializes in the treatment of mitral valve prolapse
The role of somatic symptoms in patients with depression has been historically underestimated and underrecognized. Results of the World Health Organization Collaborative Project on psychological problems in general health care have established somatization as a frequently cited feature of depression
Background. Mass psychogenic illness has been a recurrent phenomenon in Bangladesh over recent times. Objectives. This study was aimed at investigating the demographic characteristics and symptom profile of an outbreak of mass psychogenic illness occurring in a girls' high school. Methods and
A 77-year-old woman was referred to our interstitial lung disease unit. She presented with a history of progressive dyspnea on exertion and nonproductive, persistent cough over the previous year. She was diagnosed with Sjogren syndrome two years ago by a rheumatologist. In the context of Sjogren