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Systemic Absorption of Lidocaine After Hematoma Block

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When a subject with an eligible distal forearm fracture is identified, the subject will be approached for enrollment and consent. Fracture hematoma size will then be estimated using bedside ultrasound operated by trained pediatric emergency faculty or fellows. Ultrasound measurement of the

Exparel vs. Bupivacaine Hydrochloride vs. Placebo for Hernia Repair

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This will be a double-blind, 3-arm, randomized controlled trial with a treatment 1: treatment 2: control allocation ratio of 1:1:1. Primary outcomes of interest are opioid requirements and pain scores over initial 72 hours of the postoperative period. Opioid requirements will be assessed by

The Efficacy of 20 mg Parecoxib as an Adjunct to 0.75% Ropivacaine in Supraclavicular Brachial Plexus Block for Upper Limb Surgery

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Brachial plexus block (BPB) has enjoyed ubiquitous popularity for upper limb surgeries.There are a few common techniques for BPB and one of the most frequently-utilised one is supraclavicular BPB since it provides a quick-onset, efficient, safe and dense anaesthesia for surgical procedures that

Tuberculosis Infection in Women of Reproductive Age and Their Infants

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Objective The overall objective of this project is to investigate longitudinal patterns and consequences of tuberculosis (TB) infection in a prospective cohort of women recruited during pregnancy. The relation between maternal TB infection and pregnancy outcomes, as well as infant health and

A Study to Identify Biomarkers of Hypoglycaemia in Patients With Type 2 Diabetes

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Background information It is well recognised that patients with both type 1 and type 2 diabetes suffering repeated hypoglycaemia are at risk of death and significant morbidity (1). This is of major clinical importance as currently, only the recording of a low blood sugar at the time of hypoglycaemia

PK Study of EXPAREL in Subjects Undergoing Open Spinal Fusion or Reconstructive Surgery

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This is a Phase 1, multi-center, open-label study designed to evaluate the safety and pharmacokinetics of EXPAREL when administered via local wound infiltration to subjects undergoing open cervical or thoracic spinal fusion or reconstructive surgery. Fifteen subjects are planned for enrollment.

Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open Lumbar Spinal Fusion Surgery

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This is a Phase 4, multicenter, randomized, double-blind, controlled study in approximately 220 adult subjects undergoing primary, 1-2 level, open lumbar spinal fusion surgery under general anesthesia. Subjects will be screened within 30 days prior to study drug administration and at least one day

Social Inequalities in Emergency Call and Emergency Response Patterns

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Background: In prehospital emergency medicine, emergency medical dispatchers play an essential role as gatekeepers to emergency care from the emergency medical services and possibly hospital admissions. Dispatching is the task of handling emergency calls in terms of appropriate triage, delivery of

Assessment of Immediate Adverse Reactions From Dotarem in Children Under 2 Years of Age

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Our primary outcome is to assess the safety of Dotarem in these patients up to 24 hours after Dotarem injection. The patients will be monitored in the hospital for at least 2 hours following the completion of the MRI exam. Many of these patients will have received sedation for the MRI and would be

The Brain Heart Interaction in Acute Stroke

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Background On one hand structural cardiac anomalies and arrhythmias such as atrial fibrillation can give rise to thrombi that are dislodged as emboli to the brain and cause stroke. On the other hand acute emotional stress or cerebral events can cause acute cardiac dysfunction with left ventricular

Active Preoperative Anemia Management in Patients Undergoing Cardiac Surgery

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Anemia and transfusion are independent predictors of morbidity and mortality in the cardiac surgical patient population. Even so, active preoperative anemia management is not currently the standard of care at our institution. Cost associated with erythrocyte transfusions at University of Texas

Different Fluidic Strategy in Patients With Acute Abdomen : The Sure Volume

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DEPARTMENT OF GENERAL SURGERY AND SURGICAL SPECIALITIES SERVICE OF ANESTHESIOLOGY AND REANIMATION INTENSIVE CARE UNIT Head: Prof. M. Girardis MANAGEMENT OF THE PATIENT WITH ACUTE ABDOMEN SUBMITTED TO URGENT ABDOMINAL SURGERY: pilot study randomized multicentre INTRODUCTION Acute abdomen is the

Safety and Efficacy Study of Intravenous Immunoglobulin to Treat Japanese Encephalitis

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Japanese encephalitis (JE) is the most important epidemic encephalitis worldwide, causing approximately 35-50,000 cases and 10-15,000 deaths annually. Half of the survivors have severe neuropsychiatric sequelae, posing a large socio-economic burden on communities that can ill afford it. JE virus

The Symptom Experience Study in Persons With Non-Small Cell Lung Cancer

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Study Procedures: Participants will be randomly assigned (like flipping a coin) to one of the following groups upon completion of collection of initial information about the participant's: current and prior health history, symptoms, and health-related quality of life, and take a 6-minute self-paced

Maintenance Lenalidomide in Lymphoma

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Describe succinctly and clearly the past findings which justify the plan for this project. A summary of the relevant literature in the area of interest and reports of previous studies should be included. For majority of lymphoma patients who relapse after complete response or who are primary

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