constipation/breast neoplasms

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Effects of Auricular Acupressure on Constipation in Patients With Breast Cancer Receiving Chemotherapy : A Randomized Control Trial.

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The purpose was to examine the effects of auricular acupressure to relieve constipation in patients with breast cancer who were undergoing chemotherapy. Participants were 52 patients with breast cancer receiving chemotherapy at E University Hospital, Seoul, Korea, randomized into two groups of equal

Effects of a self-management program on antiemetic-induced constipation during chemotherapy among breast cancer patients: a randomized controlled clinical trial.

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Research on patient-reported outcomes indicates that constipation is a common adverse effect of chemotherapy, and the use of 5-hydroxytryptamine (serotonin; 5HT3) receptor antagonists aggravates this condition. As cancer patients take multiple drugs as a part of their clinical management, a

[Medical topics: constipation and breast cancer].

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[Simultaneous infusion of vinorelbin and taxol as first-line chemotherapy in metastasized breast cancer].

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OBJECTIVE To evaluate the activity and toxicity of simultaneous infusion of vinorelbine (VNB) and paclitaxel (T) as first line chemotherapy in advanced breast cancer patients (pts). METHODS 33 pts with histologically proven advanced breast cancer were treated with VNB 25 mg/m2 and T 150 mg/m2, both

Palliative effect of chemotherapy: objective tumor response is associated with symptom improvement in patients with metastatic breast cancer.

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OBJECTIVE Because one of the goals of chemotherapy for metastatic breast cancer is to provide symptom palliation, we were interested in identifying the relationship between tumor shrinkage and improvement in disease-related symptoms. METHODS Three hundred patients enrolled onto a randomized trial of

Phase II study of vinorelbine (alternating intravenous and oral) in combination with docetaxel as first-line chemotherapy in metastatic breast cancer.

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OBJECTIVE Combination of intravenous (i.v.) vinorelbine and docetaxel was shown to be feasible and effective in metastatic breast cancer (MBC). In an effort to improve patient convenience, we investigated in first-line treatment a regimen alternating i.v. and oral vinorelbine in combination with

Quality of life in metastatic breast cancer: comparing patients with major depressive episodes with patients without M.I.N.I. diagnosis.

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OBJECTIVE To compare the quality of life indicators in patients with metastatic breast cancer diagnosed with major depressive episodes with those in patients with no psychiatric diagnosis. METHODS We conducted a cross-sectional, observational study at the Day Care Unit of the Oncology Institute

The impact of depression and anxiety on the quality of life in nonmetastatic breast cancer patients in postoperative evaluation.

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OBJECTIVE To evaluate the impact of psychiatric comorbidities on the quality of life of early stage breast cancer subjects, in the first post-surgery week, the prevalence of those psychiatric disorders in this group, the correlation between pain and adjustment disorders and between the STAI-X1

The Effect of the Pain Symptom Cluster on Performance in Women Diagnosed with Advanced Breast Cancer: The Mediating Role of the Psychoneurological Symptom Cluster.

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BACKGROUND Pain, depression, anxiety, sleep disturbances, and constipation were reported in different symptom clusters at different stages of breast cancer. Managing symptom clusters rather than individual symptoms can improve performance status. OBJECTIVE The study examined the effect of pain

Vinorelbine (navelbine) as a salvage treatment for advanced breast cancer.

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BACKGROUND Vinorelbine (Navelbine), a new vinca alkaloid, is an effective drug in breast cancer. Our study was undertaken to assess the efficacy and tolerance of Navelbine in refractory advanced and/or metastatic breast cancer (AMBC). METHODS One hundred heavily pretreated patients with AMBC entered

Single agent vinorelbine as first-line chemotherapy in elderly patients with advanced breast cancer.

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BACKGROUND Breast cancer arises in about 48% of patients (pts) older than 65 years. Chemotherapy is administered to elderly pts with advanced breast cancer (ABC) resistant to hormonal treatment or with visceral metastases. Vinorelbine (VNR), a semisynthetic vinca alkaloid, is active and

Vinorelbine is an active antiproliferative agent in pretreated advanced breast cancer patients: a phase II study.

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OBJECTIVE To evaluate the efficacy and toxicity of single-agent vinorelbine (VNB), a semisynthetic vinca alkaloid, in patients with breast cancer previously treated with other chemotherapeutic regimens for metastatic disease. METHODS Sixty-seven of 70 patients with assessable disease entered onto

Inability to escalate vinorelbine dose intensity using a daily x3 schedule with and without filgrastim in patients with metastatic breast cancer.

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OBJECTIVE Vinorelbine (Navelbine) is a semi-synthetic vinca alkaloid with documented activity in breast cancer. The major dose-limiting toxicity (DLT) when given weekly is myelosuppression with minimal neurologic toxicity. This phase I study attempted to define the maximally tolerated dose (MTD) and

Comparison of antiemetic efficacy between single and repeated treatments with a 5-HT3 receptor antagonist in breast cancer patients with high-risk emetogenic chemotherapy.

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BACKGROUND The significance of repeated treatment with the 5-HT(3) receptor antagonist for prophylaxis of chemotherapy-induced emesis remains to be clarified. METHODS A retrospective analysis was performed to compare the effects of single and repeated treatment with granisetron on anorexia, nausea

Vincristine by continuous infusion in refractory breast cancer: a phase II study.

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Eighteen patients with advanced refractory breast carcinoma were treated with vincristine (VCR), 0.5 mg I.V. bolus followed by continuous I.V. infusions of 0.25 mg/m2/day for 5 days every 3 weeks. The daily dose of VCR was infused in 1000 ml D5W to which was added hydrocortisone 50 mg and heparin

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