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Acute esophageal necrosis after cellulitis in an obese patient with diabetes mellitus.

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A 59-year-old obese Japanese man with poorly controlled type 2 diabetes mellitus presented with severe heartburn for 3 days after inguinal cellulitis and exacerbated glycemic control, without any signs of upper gastrointestinal bleeding. The patient had a high plasma glucose level (34.0 mmol/L) and

Herniation of an abdominal antireflux fundoplication into the chest: what does it mean?

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OBJECTIVE The specific contribution of the herniation of an abdominal antireflux fundoplication into the chest to symptomatic and therefore surgical failure remains unclear. METHODS The study was conducted in 189 consecutive fundoplication patients, categorized as patients reoperated on for chest

Identification of a cell-wall peptidase (NlpC/P60) from Nocardia seriolae which induce apoptosis in fathead minnow cells.

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Nocardia seriolae, a Gram-positive bacterium, is the main pathogen of fish nocardiosis. Protein NlpC/P60 is a cell-wall peptidase and a potential virulence factor of N. seriolae. Subcellular localization research revealed that both NlpC/P60-GFP and NlpC/P60Δsig-GFP fusion proteins were evenly

Laparoscopic Nissen fundoplication: laparoscopic dissection technique and results.

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OBJECTIVE Proton Pump inhibitors and laparoscopic techniques have had a dramatic impact on the therapy of gastroesophageal reflux disease. These techniques have introduced new complications associated with the treatment. This study compares the results of a laparoscopic Nissen fundoplication with

New questions and insights into nitrate/nitrite and human health effects: a retrospective cohort study of private well users' immunological and wellness status.

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The retrospective cohort study described in this article examined 150 Iowa private well users' (aged 1-60 years) drinking water below the 10 parts per million nitrate-nitrogen (nitrate-N) maximum contaminant level and analyzed health history data and blood samples including hemoglobin fractions and

Evaluation of the routine use of the nasogastric tube in digestive operation by a prospective controlled study.

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This prospective, randomized controlled trial was undertaken to evaluate the effect of tube decompression of the stomach after surgical procedure on the digestive tract. One hundred and nine patients were randomly allocated to postoperative treatment with (57 patients) or without (52 patients)

Mechanisms of reflux-induced epithelial injuries in the esophagus.

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The esophagus is lined by a moist stratified squamous epithelium. In humans, this epithelium, as evidenced by the Bernstein test, has considerable capacity to resist damage even upon direct contact of high concentrations of luminal acid. This intrinsic property of the epithelium to defend itself

Death caused by undiagnosed acute pancreatitis.

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A fatal case of acute pancreatitis is reported. On account of difficulty in eating caused by persistent dysphagia and heartburn, the clinical condition of a 39-year-old man who had been a heavy drinker deteriorated rapidly. He was taken to a hospital in an ambulance in an unconscious state. Based on

Parietal cell vagotomy for duodenal and pyloric ulcer: clinical and secretory results.

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In the Department of Surgery, University of Turku, 310 patients underwent parietal cell vagotomy for duodenal (268 patients) or pyloric-prepyloric ulcer (42 patients) in the years 1973-82. The male/female ratio was 4/1 and mean age 43 years. There was no mortality. Splenic injury led to splenectomy

[Anti-reflux surgery: indications, principles and contribution of laparoscopy].

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Surgery is indicated when gastro-oesophageal reflux disease (GORD) is resistant to medical treatment. Manometry, upper GI series, pH-metry, gastric emptying studies and gastric acid sampling are performed in order to demonstrate that GORD is caused by a deficient gastro-oesophageal valve mechanism,

Surgical management of paraesophageal hernias: outcome and quality of life analysis.

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BACKGROUND Paraesophageal hernias (PEHs) have protean clinical manifestations, and a variety of surgical approaches may be appropriate. We report both surgical and quality-of-life (QoL) outcomes for PEH repairs. METHODS All patients undergoing elective repair of PEHs were evaluated preoperatively

Pathogenesis of gastroesophageal reflux disease.

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The pathophysiology of reflux esophagitis involves contact of the esophageal epithelium with acid-pepsin in the refluxate. For this contact to occur with sufficient duration, there must either be a combination of defects in antireflux and luminal clearance mechanisms for acid-pepsin to overwhelm a

Laparoscopic Nissen fundoplication: technique and preliminary results.

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Between May 1991 and November 1992, 80 consecutive patients with gastro-oesophageal reflux disease underwent laparoscopic Nissen fundoplication. The technique used was exactly the same as for the conventional open approach. There were no deaths but there were four peroperative complications: one

[Nissen's fundoplication by celiovideoscopy].

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One hundred and sixty two laparoscopic fundoplications were performed between may 1991 and december 1993 by the first author. No perioperative death was observed. There were 4 intraoperative complications (3%): 1 gastric perforation, 2 pleural perforations and 1 liver laceration. There were 3

Laparoscopic-thoracoscopic esophageal resection in the treatment of giant epiphrenic esophageal diverticulum (Ivor Lewis operation): Case report.

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BACKGROUND Complicated esophageal diverticulum is an extremely rare disease. The most widespread surgical tactic in such cases is drainage of the mediastinum and the position of a feeding gastrostomy or enterostomy. Our objective was to demonstrate the possibility of performing a one-step operation

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