A peritoneal function testing method of using a ratio MTAC.sub.un/MTAC.sub.c calculated using MTAC.sub.un and MTAC.sub.c as an index for a peritoneal function test. MTAC.sub.un is an overall mass transfer-area coefficient for urea nitrogen and MTAC.sub.c is an overall mass transfer-area coefficient for creatinine. Use of the MTAC.sub.un/MTAC.sub.c ratio enables examination of the future peritoneal function of a patient (a mechanism of deterioration in peritoneal function). MTAC.sub.un and MTAC.sub.c are obtained using a Pyle-Popovich model. The peritoneal function testing method further calculates a permeability coefficient for cell pores (L.sub.PS.sub.C) and an overall permeability coefficient (L.sub.PS) from a Three-Pore Theory model to obtain a ratio L.sub.PS.sub.C/L.sub.PS calculated using the L.sub.PS.sub.C and the L.sub.PS, and further uses the L.sub.PS.sub.C/L.sub.PS ratio and the MTAC.sub.un/MTAC.sub.c ratio as indexes for the peritoneal function test.

JMS Co., Ltd.

Method for testing peritoneum function and a peritoneal dialysis planning apparatus

A peritoneal function testing method uses a ratio of MTAC.sub.un/MTAC.sub.c, calculated using MTAC.sub.un and MTAC.sub.c, as an index for a peritoneal function test, wherein MTAC.sub.un is an overall mass transfer-area coefficient for urea nitrogen and MTAC.sub.un is an overall mass transfer-area coefficient for creatinine. The use of MTAC.sub.un/MTAC.sub.c enables examination of the future peritoneal function of a patient (a mechanism of deterioration in peritoneal function). To be specific, MTAC.sub.un and MTAC.sub.c can be obtained by computing a Pyle-Popovich model. In addition, the peritoneal function testing method further calculates a permeability coefficient for cell pores (L.sub.pS.sub.C) and an overall permeability coefficient (L.sub.PS) from a Three-Pore Theory model while obtaining a ratio of L.sub.PS.sub.C/L.sub.PS calculated using the L.sub.PS.sub.C and the L.sub.PS. The L.sub.PS.sub.C/L.sub.PS ratio and the MTAC.sub.un/MTAC.sub.c ratio can be used as indexes for the peritoneal function test.

Hamada; Hiroyuki

Okamoto; Masahiro

The present invention is a peritoneal function testing method characterized by using a ratio MTAC.sub.un/MTAC.sub.c calculated using MTAC.sub.un and MTAC.sub.c as an index for a peritoneal function test, where MTAC.sub.un is an overall mass transfer-area coefficient for urea nitrogen and MTAC.sub.c is an overall mass transfer-area coefficient for creatinine. The use of MTAC.sub.un/.sub.c of the present invention in this way enables examination of the future peritoneal function of a patient (a mechanism of deterioration in peritoneal function). To be specific, MTAC.sub.un and MTAC.sub.c can be obtained by computing Pyle-Popovich model. In addition, the peritoneal function testing method may further calculate a permeability coefficient for cell pores (L.sub.PS.sub.C) and an overall permeability coefficient (L.sub.PS) from Three-Pore Theory model while obtaining a ratio L.sub.PS.sub.C/L.sub.PS calculated using the L.sub.PS.sub.C and the L.sub.PS, and may use the L.sub.PS.sub.C/L.sub.PS ratio and the MTAC.sub.un/MTAC.sub.c ratio as indexes for the peritoneal function test.

A cytobiotic of cytogenic globulin for the treatment of kidney disorders in mammalian subjects and for prophylaxis against kidney-cell degeneration and as a cell regenerative treatment, comprises the product obtained by recovering renal tissue from slaughterhouse animals, obtaining an extract therefrom and using this extract to innoculate a horse and obtain an immunological response plasma. From the latter zinc salt or ammonium sulfate is used to obtain a precipitate which, after dialysis, leads to a dialysate which contains the effective globulins.

Omnium Financier Aquitaine pour l'Hygiene et la Sante

(Courbevoie, FR

Cytobiotic globulins for kidney treatment

This disclosure recognizes the fact that the technology of making vesicles from lecithin and lecithin-like molecules, although well known and highly developed, is associated with problems of instability. It is known that vesicles coalesce, rupture and spill their contents long before the vesicle is used for its intended purpose.It has been discovered and disclosed herein that the deterioration of the vesicle delivery system is due in part to the rupture of the bipolar lipid vesicle membrane by the contents of the core volume or by an external agent. For example, the more detergent-like the properties of the pharmacological agent within the vesicle core volume, the more pronounced will be the attack on the vesicle wall interior. These events in turn will lead to vesicle membrane rupture.This disclosure sets forth the proper manufacturing techniques to achieve vesicle stability following the discovery and also discloses a large-scale experiment which fully establishes the function taking place microscopically in the true vesicle. The experiment designed to substantiate the discovery is one using visible sized dialysis bags to show that gelatinized pharmacological agents are capable of existing without disruption in the appropriate solutions. The dialysis bag could not be used in the administration of a pharmacological agent to a person but illustrates on a large-scale what takes place microscopically in the actual vesicle environment.

hemodialysis/atrophy

Method for testing peritoneum function and a peritoneal dialysis planning apparatus

Method for testing peritoneum function and a peritoneal dialysis planning apparatus

Method for testing peritoneum function and a peritoneal dialysis planning apparatus

Cytobiotic globulins for kidney treatment

Gelcores

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