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hemodialysis/infarction

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Compositions and methods for inhibiting thrombogenesis

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FIELD OF THE INVENTION The present invention relates generally to compositions and methods for the treatment of cardiovascular disease. More particularly, the present invention relates to modifying thrombus formation and growth by administering a heparin cofactor II-specific (HCII) catalytic agent

Compositions and methods for inhibiting thrombogenesis

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FIELD OF THE INVENTION The present invention relates generally to compositions and methods for the treatment of cardiovascular disease. More particularly, the present invention relates to modifying thrombus formation and growth by administering an agent capable of selectively inactivating thrombin

Compositions and methods for inhibiting thrombogenesis

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FIELD OF THE INVENTION The present invention relates generally to compositions and methods for the treatment of cardiovascular disease. More particularly, the present invention relates to modifying thrombus formation and growth by administering an agent which, inter alia, is capable of (1)
BACKGROUND OF THE INVENTION It has been more than four decades since the introduction of heparin, warfarin and indandione derivatives for the treatment and preventing of thromboembolic disorders. These drugs remain to be the only effective anticoagulants in use today. They exert their effects by

Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics

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FIELD OF THE INVENTION The present invention relates generally to processes for the preparation of low affinity, low molecular weight heparins (LA-LMW-heparins) which are useful, inter alia, as antithrombotics. More particularly, the present invention relates to processes for the preparation of

Modified low molecular weight heparin that inhibits clot associated coagulation factors

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FIELD OF THE INVENTION The present invention relates generally to compositions and methods for the treatment of cardiovascular disease. More particularly, the present invention relates to modifying thrombus formation and growth by administering a modified low molecular weight heparin (MLMWH) that,
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