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New efficient eco-friendly supported catalysts for the synthesis of amides with antioxidant and anti-inflammatory properties.

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New environment friendly approach for the synthesis of idrocilamide (1), the marketed myorelaxant and anti-inflammatory agent, is reported. The synthetic strategy involves a solvent free aminolysis reaction catalyzed by different zinc-containing catalysts: ZnCl2, montmorillonite K10 impregnated with

Antioxidant, anti-inflammatory and anti-septic potential of phenolic acids and flavonoid fractions isolated from Lolium multiflorum.

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BACKGROUND Interest has recently renewed in using Lolium multiflorum Lam. (Poaceae) (called Italian ryegrass; IRG) silage as an antioxidant and anti-inflammatory diet. OBJECTIVE This study investigated the antioxidant, anti-inflammatory and anti-septic potential of IRG silage and identified the

Increased numbers of Th2-like CD4+ T cells in target organs and in the allergen-specific repertoire of allergic patients. Possible role of IL-4 produced by non-T cells.

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Phytohemagglutinin (PHA)-induced human T cell clones (TCC) derived from conjunctival flogistic tissues of 3 patients with vernal conjunctivitis produced unusually high amounts of interleukin-4 (IL-4) and no, or limited amounts of, gamma-interferon (IFN-gamma). Allergen (Dermatophagoides

Substrate preference profiles of proteases released by allergenic pollens.

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BACKGROUND Pollens are important triggers for allergic asthma and seasonal rhinitis. We have recently reported that proteases released by major allergenic pollens can injure airway epithelial cells in vitro. Disruption of epithelial integrity by proteases released following deposition of pollens on

[Allergens and risk factors in pediatric patients with allergic seasonal conjunctivitis].

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BACKGROUND The seasonal allergic conjunctivitis is an inflammatory disease of the ocular surface that affects mainly children, with predominance of male sex. It is an immunological disease with a typical reaction of hypersensitivity type 1 (IgE), resulted from several biological reactions

Further investigation of equine fescue oedema induced by Mediterranean tall fescue (Lolium arundinaceum) infected with selected fungal endophytes (Epichloë coenophiala).

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AIMS To determine if equine fescue oedema (EFO) induced by grazing Mediterranean-type tall fescue (Lolium arundinaceum) infected with selected endophytes (Epichloë coenophiala) could be prevented by treatment with the corticosteroid, methylprednisolone, and anti-histamine, cetirizine, and to

Local allergic rhinitis in children: Novel diagnostic features and potential biomarkers.

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BACKGROUND Local allergic rhinitis (LAR) is a phenotype of rhinitis that has been poorly studied in children. It is characterized by the same symptoms of allergic rhinitis but with the absence of markers of systemic atopy. OBJECTIVE To identify children affected by LAR and to analyze the

Nasal lavage cytology and mucosal histopathological alterations in patients with rhinitis.

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The extent of epithelial lesion in allergic and non-allergic rhinitis and its association with inflammatory changes in nasal lavage has not been clarified.To verify the association between the inflammatory cells in the nasal lavage, epithelial lesion extent

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Herbal & Natural Medicine

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