Natural Product Research 2017-Feb
A new furanocoumarin from the fruits of Scaevola taccada and antifungal activity against Pythium insidiosum.
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A new coumarin, scataccanol (1) and 10 known compounds were isolated from the fruits of Scaevola taccada (Gaertn.) Roxb. All compounds were evaluated for antifungal activity against Pythium insidiosum. Compounds 5 and 7 showed strong antifungal activity with minimum inhibitory concentration values of 5 and 10 μg/mL, respectively. Structural determination of all compounds was accomplished by 1D and 2D-NMR, IR and MS.