Journal of Clinical Pharmacy and Therapeutics 2017-Oct
Aggravated nausea and vomiting induced by fat emulsion for hyperemesis gravidarum: A case report.
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OBJECTIVE
Total parental nutrition (TPN) for hyperemesis gravidarum (HG) is generally effective and well-tolerated. We report a case of aggravated nausea and vomiting caused by fat emulsion.
METHODS
A 40-year-old pregnant woman through IVF was admitted to the hospital at 11-week gestation and diagnosed with HG. During TPN treatment, the patient suffered from aggravated nausea and vomiting. We identified fat emulsion as the most likely culprit using challenge, dechallenge and rechallenge.
CONCLUSIONS
This is the first report of fat emulsion aggravating nausea and vomiting in such situation.
