Hypertension in Pregnancy 2015-May
Evaluation of cord blood ischemia modified albumin in normal pregnancies and pre-eclampsia.
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Abstrakcyjny
OBJECTIVE
Pre-eclampsia is associated with ischemia and increased oxidative stress, which may lead to modification of plasma albumin to ischemia modified albumin (IMA).
METHODS
IMA levels were estimated in cord blood of 30 newborns born to pre-eclamptic mothers and compared with 30 normal newborns. IMA was estimated colorimetrically and the results were compared statistically.
RESULTS
The levels of IMA were found to be significantly higher (p < 0.001) in newborns born to pre-eclamptic mothers (0.835 ± 0.02 ABSU) as compared to those born to normal mothers (0.325 ± 0.01 ABSU).
CONCLUSIONS
IMA may act as a marker of ischemia and oxidative stress in newborns delivered to pre-eclamptic mothers.
