[Late mediastinal hematoma presenting cardiac tamponade after re-do off-pump coronary artery bypass grafting in octogenarian; report of a case].

An 86-year-old man was admitted to our hospital with angina due to the instent restenosis. He had a history of coronary artery bypass grafting( CABG). Re-do off-pump CABG was performed. Aspirin and warfarin were started on the next day. The drainage tubes were removed on the postoperative day (POD) 2 and clopidogrel was resumed. On POD 9, he complained of nausea and dyspnea even at rest. Chest computed tomography (CT) and transthoracic echocardiography showed anterior mediastinal hematoma. 550 ml bloody effusion was discharged by percutaneous drainage. Because the accumulation of the mediastinal fluid was mainly anterior to the pericardial space, it was thought to be due to oozing from the sternum and soft tissues. The cause was unclear, but both antiplatelet and anticoagulant agents could have caused the oozing. He was discharged without reaccumulation of the effusion. It is important to take account of such delayed complications when multiple antiplatelet and anticoagulant agents are used after cardiovascular surgery especially in the octogenarian.