World Journal of Pediatrics 2014-Aug
Lemierre's syndrome with double heterozygote status in the methylenetetrahydrofolate reductase gene.
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Abstrakcyjny
BACKGROUND
There are some risk factors being more vulnerable to Lemierre's syndrome such as a hypercoagulable state.
METHODS
We report a rare case of Lemierre's syndrome with ethmoid and maxillary sinusitis, bilateral mastoiditis, and sigmoid sinus thrombosis.
RESULTS
Genetic study revealed a double heterozygote status in the methylenetetrahydrofolate reductase gene including C677T and A1298C.
CONCLUSIONS
It is suggested to screen patients with Lemierre's syndrome for a hypercoagulable state to consider anticoagulant therapy.
