Canadian Veterinary Journal 1999-Apr
Observations on the use of tetracycline and niacinamide as antipruritic agents in atopic dogs.
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Tetracycline and niacinamide were administered in combination to 19 atopic dogs to determine their effectiveness in controlling pruritus. The pruritus was controlled successfully in only one dog. One dog experienced diarrhea that was severe enough to warrant stopping the medication.