World Neurosurgery 2020-Mar
Oxygen embolism and pneumocephalus after hydrogen peroxide application during minimally invasive transforaminal lumbar interbody fusion surgery: A case report and literature review.
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BACKGROUND
Hydrogen peroxide (H2O2) solution is commonly used to irrigate wounds because of its hemostatic and antiseptic properties. Previous studies suggest that H2O2 can result in toxicity to keratinocytes and fibroblasts, but complications after H2O2 application, including oxygen embolism, which is one of the most severe, have rarely been reported.