11 wyniki
BACKGROUND OF THE INVENTION
Adenosine is an extracellular messenger generated by all cells in the body. Adenosine itself, substances that mimic the actions of adenosine, and substances that antagonize its actions have important clinical applications. In the heart, an organ whose function depends
FIELD OF THE INVENTION
The present invention relates to novel compounds that are partial or full A.sub.1 adenosine receptor agonists, and to their use in treating mammals for various disease states, including modifying cardiac activity, in particular treatment of arrhythmia. The compounds are also
FIELD OF THE INVENTION
The present invention relates to novel compounds that are A.sub.1 adenosine receptor agonists, and to their use in treating mammals for various disease states, including modifying cardiac activity, in particular treatment of arrhythmia. The compounds are also useful for
FIELD OF THE INVENTION
The present invention relates to novel compounds that are partial or full A.sub.1 adenosine receptor agonists, and to their use in treating mammals for various disease states, including modifying cardiac activity, in particular treatment of arrhythmia. The compounds are also
FIELD OF THE INVENTION
The present invention relates to the preparation of compounds that are partial or full A.sub.1 adenosine receptor agonists. The compounds are useful for treating mammals with diabetic disorders, obesity, modifying adipocyte function, CNS disorders, and modifying cardiac
FIELD OF THE INVENTION
The present invention relates to novel compounds that are partial or full A.sub.1 adenosine receptor agonists, and to their use in treating mammals for various disease states, including modifying cardiac activity, in particular treatment of arrhythmia. The compounds are also
FIELD OF THE INVENTION
The present invention relates to the preparation of compounds that are partial or full A.sub.1 adenosine receptor agonists. The compounds are useful for treating mammals with diabetic disorders, obesity, modifying adipocyte function, CNS disorders, and modifying cardiac
FIELD OF THE INVENTION
The present invention relates to novel compounds that are partial or full A.sub.1 adenosine receptor agonists, and to their use in treating mammals for various disease states, including modifying cardiac activity, in particular treatment of arrhythmia. The compounds are also
FIELD OF THE INVENTION
The present invention relates to novel compounds that are partial or full A.sub.1 adenosine receptor agonists, and to their use in treating mammals for various disease states, including modifying cardiac activity, in particular treatment of arrhythmia. The compounds are also
FIELD OF THE INVENTION
The present invention relates to novel compounds that are partial or full A.sub.1 adenosine receptor agonists, and to their use in treating mammals for various disease states, including cardiovascular diseases, in particular arrhythmia, and the prevention of sudden death
FIELD OF THE INVENTION
The present invention relates to novel compounds that are partial or full A.sub.1 adenosine receptor agonists, and to their use in treating mammals for various disease states, including cardiovascular diseases, in particular arrhythmia, and the prevention of sudden death