Compositions and method for treating conditions in humans associated with symptoms of unspecified retarded maturation due to chromosomal abnormalities cerebral atrophy, Huntington's Chorea, Alzheimer's disease and the like wherein the composition comprises a) at least one of haloperidol, imipramine and trifluoperazine, b) gamma butyric acid, c) phenylalamine, d) an antioxidant, e) folic acid, f) nicotinamide or its salt and g) a lithium salt. The composition can additionally contain a benzodiazepine and is administered orally.

Composition and method for treating conditions associated with symptoms of unspecified retarded maturation

Formulations are provided for the treatment of patients suffering from disorders that have in common the appearance of muscular hypotonia as a symptom. These disorders include Alzheimer's type diseases, atrophy of the brain, atrophy of the cerebellum, Fragile X syndrome, mental retardation of unknown causes, multiple anomalies in the chromosomes, deletions in one or more chromosome, and fragility in a chromosome other than the X chromosome. The formulations of the invention contain therapeutically effective amounts of gamma amino butyric acid (GABA), an anti-oxidant (such as ascorbic acid and/or vitamin E), folic acid, nicotinamide, and a lithium salt, all in a pharmaceutically acceptable excipient. Methods for the treatment of these disorders by the administration of such formulations are also provided.

Bleiweiss; Herman

Bleiweiss; Eduardo Samuel

butyric acid/atrofia

Composition and method for treating conditions associated with symptoms of unspecified retarded maturation

Pharmaceutical formulations and methods for treating patients suffering from diseases that cause muscular hypotonia

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