surgical repair through the classic technique (Milligan and Morgan technique)

Hemorrhoidal Disease

upper rectal artery embolization with coils

embolization

surgical repair

Hospital Israelita Albert Einstein

Upper Rectal Artery Embolization in the Treatment of Hemorrhoidal Disease

To determine the feasibility of implementing upper rectal artery embolization in the treatment of patients with grade 2 (protrude beyond the anal verge with straining or defecating but reduce spontaneously) and 3 hemorrhoids (protrude spontaneously or with straining and require manual reduction), relating its short- and long-term outcomes with patients undergoing surgical repair through the classic technique (Milligan and Morgan technique).

To assess the impact of upper rectal artery embolization on the treatment of chronic bleeding secondary to hemorrhoidal disease, on clinical success rate.

To assess the impact of upper rectal artery embolization on the treatment of chronic bleeding secondary to hemorrhoidal disease, on need of retreatment.

To assess the impact of upper rectal artery embolization on the treatment of chronic bleeding secondary to hemorrhoidal disease, on symptom relapse

To assess the impact of embolization on the time required for clinical recovery and return to daily activities

Pharmacoeconomic assessment of the comparison between upper rectal artery embolization methods for hemorrhoidal disease treatment and conventional surgical treatment

About 60 patients will be considered to be in control group receiving vaseline ointment as the placebo applying 2 times daily on their ulcers for 8 weeks.

About 30 patients will receive Diltiazem Gel 2% applying 2 times daily for 8 weeks on their digital ulcers.

About 30 patients will receive nitroglycerin 2% applying 2 times daily for 8 weeks on their digital ulcers.

Digital Ulcer of Scleroderma

This a topical agent which will be applied on digital ulcers by scleroderma patients.

Diltiazem Gel 2%

Nitroglycerin Ointment 2%

This is used as the topical placebo agent.

Vaseline

Rheumatology Reseach Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Diltiazem Gel Versus Nitroglycerin Ointment in Healing Process of Scleroderma Digital Ulcers

Assessing and Comparing the Effect of Diltiazem Gel Versus Nitroglycerin Ointment in Healing Process of Scleroderma Digital Ulcers.

The individual characteristic and information of the patients will be preserved by the researches and won't be released.

fissure in ano/obrzęk

Upper Rectal Artery Embolization in the Treatment of Hemorrhoidal Disease

Diltiazem Gel Versus Nitroglycerin Ointment in Healing Process of Scleroderma Digital Ulcers

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