Patient will receive 30ml of Gastrografin (diluted at 1:3 ratio with water) as recommended by the manufacturer for a single dose in our population. The dose will be given via the nasogastric tube, which will then be clamped for 1 hour. Gastrografin will only be given if there is evidence of a bowel obstruction. Additionally, Gastrografin will only be given when the patient is hemodynamically stable, not receiving any inotropes, and off of invasive respiratory support. Once administered the patient will receive an x-ray at 48 hours. If Gastrografin can be viewed past the obstruction than another dose of Gastrografin (30ml at 1:3 dilution ratio with water via NG tube) can be given. If gastrografin is not viewed past the obstruction than another dose will not be given.
Generic name: Diatrizoate Meglumine, Diatrizoate Sodium

This group will be recruited from an ongoing observational study at our centre. The patients in this group have all received the standard care for treating gastroschisis and any potentially associated bowel obstruction. They have not received Gastrografin. They will be recruited between May 2010 and May 2019.

Gastroschisis

Bowel Obstruction

Birth Defect

Gastrografin

Children's Hospital, London Health Sciences Centre

The Use of Gastrografin to Help Alleviate Bowel Obstruction in Gastroschisis Patients.

The Use of Gastrografin to Help Alleviate Bowel Obstruction Related to Poor Bowel Motility in Gastroschisis Patients.

The length of time in days from admission/birth to initiate feeding.

The length of time in days from when feeding was initiated to when baby is considered fully fed

The time between admission/birth to discharge

The rate of other such complications associated with gastroschisis or Gastrografin during hospital stay

The rate of elective surgeries in both groups to treat bowel obstruction during hospital stay

Lawson Health Research Institute

32 weeks to 36 weeks 6 days old of post menstrual age infants, feeding intolerants monitored with INVOS device for rSO2

32 weeks to 36 weeks 6 days old of post menstrual age infants without problems through the enteral feedings.

Feeding Intolerance

Necrotizing Enterocolitis

Premature Infant

Evaluation of Feeding Intolerance in Premature Infants Using Near Infrared Spectroscopy

There is not an specific threshold of regional oxygen saturation measured through NIRS, the investigators want to evaluate the range of saturation as follows: 1. Greater than 0.60; 2. .50 to .60 and less than 0.50 Oxygen saturation, reading above expected, expected, below expected respectively.

NIRS Cerebral Oxygenation and Splanchnic Oxygenation help to obtain an index where 0.75 to 0.95 could be considering adequate and below 0.75 considered abnormal. Area under the ROC curve is needed.

gastroschisis/wymioty

The Use of Gastrografin to Help Alleviate Bowel Obstruction in Gastroschisis Patients.

Evaluation of Feeding Intolerance in Premature Infants Using Near Infrared Spectroscopy

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