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FIELD OF THE INVENTION
This invention relates to cyanamide compounds useful as reversible inhibitors of the cysteine proteases cathepsins S, K, F, L and B. Certain embodiments described are preferable for inhibition of cathepsin K. The compounds are therefore useful in the treatment of cysteine
FIELD OF THE INVENTION
This invention relates to peptidyl carbamates and related compounds. The compounds are reversible inhibitors of the cysteine proteases cathepsins S, K, F, L and B and certain embodiments described are preferable for inhibition of cathepsin K. The compounds are therefore useful
TECHNICAL FIELD
The invention relates to methods and materials for treating inflammatory conditions. More specifically, the invention relates to using modulators of kallikrein 6 protease activity to treat inflammatory conditions such as multiple sclerosis.
BACKGROUND
Multiple Sclerosis (MS) is a
FIELD OF THE INVENTION
This invention relates to novel .alpha.-aminoketone derivatives and, in particular, to novel .alpha.-aminoketone derivatives and their pharmaceutically acceptable salts which strongly inhibit thiol protease such as papain, cathepsin B, cathepsin H, cathepsin L and calpain or