A quinolone antibacterial compound, or a salt or hydrate of the compound, for the treatment of infectious diseases, which exhibit potent antibacterial activity and higher selective toxicity against Gram-positive and Gram-negative bacteria, which do not cause side effects (e.g., convulsion), which exhibit higher safety, and which has a structure of formula (I): ##STR00001##

Takahashi; Hisashi

Kuroyanagi; Junichi

Miyauchi; Rie

Nagamochi; Masatoshi

Takemura; Makoto

Hayakawa; Isao

Daiichi Sankyo Company, Limited

Substituted pyrrolidine derivative

Certain cis-N-(2-amino-cycloalophatic)benzamides of the formula ##STR1## where m is 0, n is 2, r is alkyl, R.sub.1 and R.sub.2 are taken together with the nitrogen denote a pyrrolidine ring, X and Y are hydrogen or a halogen having an atomic number of from 9 to 35, e.g., cis-3,4-dichloro-N-methyl-n[2-(1-pyrrolidinyl)cyclohexyl]benzamide, and salts thereof, have been found to have CNS seizure blocking or preventing drug action, e.g., anti-convulsant drug properties with little or no analgesic properties.

pyrrolidine/napad padaczkowy

Substituted pyrrolidine derivative

Substituted pyrrolidine derivative

Cis-N-(2-aminocycloaliphatic)benzamide anti-convulsants

Najbardziej kompletna baza danych ziół leczniczych poparta naukowo