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The present invention relates to a method of treating or preventing a disorder selected from stroke, epilepsy, head trauma, spinal cord trauma, ischemic neuronal damage such as cerebral ischemic damage from stroke or vascular occlusion (e.cf, during open heart surgery), excitotoxic neuronal damage
BACKGROUND OF THE INVENTION
The present invention relates to aromatic pyrrolidine and thiazolidine amides, to pharmaceutical compositions comprising such compounds, to methods of preparing such compounds, and to the use of such compounds for enhancing learning behavior and memory and in the
BACKGROUND OF THE INVENTION
The present invention relates to aromatic pyrrolidine and thiazolidine amides, to pharmaceutical compositions comprising such compounds, to methods of preparing such compounds, and to the use of such compounds for enhancing learning behavior and memory and in the
This invention relates to derivatives of 1,4-diydroqainoxalin-2,3-dione which are selective antagonists of N-methyl-D-aspartate receptors.
BACKGROUND OF THE INVENTION
L-Glutamic acid is an excitatory amino acid neurotransmitter whose physiological role in the brain involves interaction with four
TECHNICAL FIELD
The present invention relates to a novel butadiene derivative and a novel pyrrolidine derivative, both having excellent activity for inhibiting the activity or production of type 1 plasminogen activator inhibitor (PAI-1) in living body and being useful as an antithrombotic agent, and