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respiratory insufficiency/hypoxia
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Cerebral and ventilatory depression during hypoxia in anaesthetized newborn guinea-pigs.
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The effects of hypoxia on ventilation and cerebral activity were studied in urethane-anaesthetized newborn guinea-pigs. Ventilation was measured by a pneumotachograph, and cerebral activity by a cerebral function monitor (CFM). All animals were subjected to either 9% O2 or 6% O2 in N2 for 10 minutes
[Effectiveness of the HighFO novel oxygen nebulizer for respiratory failure patients with severe hypoxia].
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Optimal oxygen delivery is an essential component of therapy for patients with respiratory failure. Reservoir masks or air entrainment nebulizers have often been used for patients who require highly concentrated oxygen, but these may not actually deliver a sufficient fraction of inspired oxygen if
Decreased energy metabolism in brain stem during central respiratory depression in response to hypoxia.
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Metabolic changes in the brain stem were measured at the time when oxygen deprivation-induced respiratory depression occurred. Eucapnic ventilation with 8% oxygen in vagotomized urethan-anesthetized rats resulted in cessation of respiratory drive, monitored by recording diaphragm electromyographic
Naloxone reduces ventilatory depression of brain hypoxia.
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To assess whether endogenous opioids participate in respiratory depression due to brain hypoxia, we determined the ventilatory response to progressive carboxyhemoglobinemia (1% CO, 40% O2) before and after administration of naloxone (NLX, 0.1 mg/kg iv). Minute ventilation (VI) and ventral medullary
Unrecognized hypoxia and respiratory depression in emergency department patients sedated for psychomotor agitation: pilot study.
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BACKGROUND
The incidence of respiratory depression in patients who are chemically sedated in the emergency department (ED) is not well understood. As the drugs used for chemical restraint are respiratory depressants, improving respiratory monitoring practice in the ED may be warranted. The objective
Respiratory failure associated with familial depression of ventilatory response to hypoxia and hypercapnia.
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Respiratory failure has been associated with depressed ventilatory responses to hypoxia or hypercapnia or both. The possibility that familial factors are responsible for decreased chemosensitivity prompted this study of a child with unexplained respiratory failure and normal lung function. We found
Dark adaptation during systemic hypoxia induced by chronic respiratory insufficiency.
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OBJECTIVE
To investigate dark adaptation during hypoxia in patients with chronic respiratory failure.
METHODS
At three visits, dark adaptation was recorded by computerized dark adaptometry in 13 patients with chronic respiratory insufficiency treated by long-term oxygen therapy. At visits 1 and 3,
Nerve conduction impairment in patients with respiratory insufficiency and severe chronic hypoxemia.
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Sixteen patients with chronic respiratory insufficiency and severe hypoxemia were studied to determine the effect of chronic respiratory insufficiency on peripheral sensory and motor nerve conduction. When matched with a control group, a statistically significant slowing (from p less than 0.02 to p
No effect of naloxone on hypoxia-induced ventilatory depression in adults.
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The ventilatory response to acute isocapnic hypoxia is prompt but is not maintained at its peak. Within 10 min, it begins to fall, and by 30 min has reached an approximately steady level, usually still above control. We used naloxone to test in four men the hypothesis that this fade is hypoxic
Ventilatory responses to hypoxia and hypercapnia in asthmatics with previous respiratory failure.
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The ventilatory response to hypoxia and the ventilatory and mouth occlusion pressure response to hypercapnia was measured in 13 subjects who had previously developed respiratory failure or respiratory arrest during an acute asthma attack. In 11 of 12 subjects tested there was a normal response to
Hypoxemia during bilevel positive airway pressure treatment in patients with obstructive sleep apnea syndrome and chronic respiratory insufficiency.
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In patients with obstructive sleep apnea (OSA) syndrome and chronic respiratory insufficiency one of the options of treatment is bilevel positive airway pressure (BPAP) during sleep. The aim of the study was to find out what are the factors influencing the early results of BPAP treatment in such OSA
[Intensive care of respiratory insufficiency and hypoxia].
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Analysis of the results of studies carried out in 1200 patients aged 1 day to 75 years hospitalized at reanimation and intensive care wards for critical and terminal states of different origin showed that respiratory insufficiency and hypoxia play the main role in the pathogenesis of critical states
Diagnostic Bedside Ultrasonography for Acute Respiratory Failure and Severe Hypoxemia in the Medical Intensive Care Unit: Basics and Comprehensive Approaches.
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Bedside goal-directed ultrasound is a powerful tool for rapid differential diagnosis and monitoring of cardiopulmonary disease in the critically ill patient population. The bedside intensivist is in a unique position to integrate ultrasound findings with the overall clinical situation. Medically
Impact of systemic hypoxemia on cancer aggressiveness and circulating vascular endothelial growth factors A and C in gastroesophageal cancer patients with chronic respiratory insufficiency.
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OBJECTIVE
Due to the common etiologic factor, a considerable number of esophagogastric cancer patients suffer from respiratory insufficiency in course of chronic obstructive pulmonary disease, primary to cancer. Systemic hypoxemia may account for poor oxygenation of tumor tissue-a main driving force
Effects of aminophylline on hypoxemia-induced ventilatory depression in the cat.
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We designed experiments to evaluate changes in ventral medullary (VM) extracellular fluid (ECF) PCO2 and pH during hypoxemia-induced ventilatory depression (VD). Our aim was to investigate effects of aminophylline on VD and VM ECF acid-base variables. We used aminophylline because it inhibits
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