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ricinus/lek przeciwnowotworowy

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ArtykułyBadania klinicznePatenty
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ZnO nanoparticles have been synthesized using solution combustion technique and its antioxidant, antifungal, anticancer activity was studied. Ricinus communis plant seed extract used as fuel in synthesis by the solution combustion technique. Powder X-ray diffraction (PXRD) demonstrates the

The toxicity and antitumor activity of three individual fractions of lectins from Ricinus communis seeds.

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Lectins from Ricinus communis seeds (RCL) have been resolved into three electrophoretically distinct fractions (alpha-RCL, beta-RCL, psi-RCL) by ion exchange chromatography on Watman CM-32 cellulose. The toxicity to mice and antitumor activity against murine lymphoma NK/Ly of pure fractions were

Studies on the antitumor lectins isolated from the seeds of Ricinus communis (castor bean).

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Three toxic proteins and one agglutinin were purified from the seeds of Ricinus communis by a simple and fast method using Sepharose 4-B affinity chromatography followed by Sephadex G-100 gel filtration. The weakly adsorbed ricins A and B were retarded and eluted with the buffer from the affinity

Anti-tumour necrosis factor-alpha activity in Ixodes ricinus saliva.

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Tumour necrosis factor-alpha (TNF-alpha) is one of the most prominent inflammatory mediators playing a central role in starting off the inflammatory reactions of the innate immune system. We identified a TNF-alpha-inhibitory activity in the saliva and salivary gland extract (SGE) from partially fed

Crystalline ricin D, a toxic anti-tumor lectin from seeds of Ricinus communis.

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A toxic lectin, ricin D, present in the seeds of Ricinus communis has been purified and crystallized in a form suitable for high resolution crystallographic structure studies. This protein is different from a previously found form of ricin (also present in the same seeds), the only ricin for which a

[Isolation of cytostatically active proteins from seeds of Ricinus communis, Abrus praecatorius and Canavalia ensiformis (author's transl)].

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The extraction and isolation of, as yet, uninvestigated antitumor active protein mixtures from the seeds of Abrus praecatorius, Canavalia ensiformis and especially Ricinus communis is reported. By means of membrane ultrafiltration of crude ricin a low-molecular weight protein mixture, Ro 413, could

Extraction and partial purification of ricin from Ricinus communis L.

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Ricinus communis L., usually cultivated for production of oil, has some use in medicine, cosmetic industries and as motor oil. The defatted seed meal is very toxic, and can not be used as human or animal food. This study undertook extraction and identification of ricin, a toxalbumine, from Iranian

Essential oil of the leaves of Ricinus communis L.: in vitro cytotoxicity and antimicrobial properties.

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BACKGROUND The aim of the present study was to appraise the antimicrobial activity of Ricinus communis L. essential oil against different pathogenic microorganisms and the cytotoxic activity against HeLa cell lines. METHODS The agar disk diffusion method was used to study the antibacterial activity
BACKGROUND Ricinus communis (Euphorbiaceae) has previously been reported to possess analgesic, antihistamine, antioxidant and anti-inflammatory activities. This study was designed for isolation, characterization and evaluation of antibacterial and anti-proliferative activities of R. communis seed
While probably originating from Africa, the plant Ricinus communis is found nowadays around the world, grown for industrial use as a source of castor oil production, wildly sprouting in many regions, or used as ornamental plant. As regards its pharmacological utility, a variety of medical purposes

An extract from Ricinus communis L. leaves possesses cytotoxic properties and induces apoptosis in SK-MEL-28 human melanoma cells.

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Plants are an important source of several clinically useful anti-cancer agents. A volatile extract was obtained from Ricinus communis L. (Euphorbiaceae) leaves by standard hydrodistillation and subsequent extraction of the cohobated water in chloroform. GC-MS identified three monoterpenoids:

Ricinus communis L. fruit extract inhibits migration/invasion, induces apoptosis in breast cancer cells and arrests tumor progression in vivo.

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Medicinal plant-based therapies can be important for treatment of cancer owing to high efficiency, low cost and minimal side effects. Here, we report the anti-cancer efficacy of Ricinus communis L. fruit extract (RCFE) using estrogen positive MCF-7 and highly aggressive, triple negative MDA-MB-231
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