Stroke

Cannabis Use

Drug urinal test

Chu Jean Minjoz

Unite Neuro-Vasculaire

Chu Bocage

C.H. G. Muller

Hopital Central

Les Hôpitaux Universitaires de Strasbourg

Prevalence of Strokes Secondary to a Reversible Cerebral Vasoconstriction Attributable to Cannabis Consumption in Young Subjects (≤ 45 Years) Hospitalized for an Ischaemic Stroke

medical imaging of intracranial arteries will show new stenoses (topography, number, evolution), and new ischemic or cerebral haemorrhagic lesions

University Hospital, Strasbourg, France

Pediatric epilepsy patients who are followed at Children's Hospital Colorado with medically refractory epilepsy, and whom the family has decided to treat with medical cannabis.

Epilepsy, Unspecified, Refractory (Medically)

Pediatric patients with medically refractory epilepsy and treated with medicinal cannabis.

Medical Cannabis

More information about medical marijuana research at childrens hospital colorado

Children's Hospital Colorado

The Use of Medicinal Cannabinoids as Adjunctive Treatment for Medically Refractory Epilepsy

Prolonged EEG recordings lasting 24-48 hours (whichever is clinically indicated) will be performed in either the home setting as an ambulatory EEG or in the hospital in the Epilepsy Monitoring Unit. This decision will be made on a clinical basis. This will allow for objective quantification of seizures in children with frequent seizures that occur on a daily basis and background EEG changes for other children. Two EEGs will be done: one at baseline, and one at the end of the study.

Each subject will maintain a seizure diary. Rescue drug use and VNS (Vagus Nerve Stimulation) activations will be tracked as an adjunct to all current anti-seizure medications. Frequency of status epilepticus will be tracked as well as hospital visits for seizures or adverse events from MCBD. Clinical evaluations will be taken every 2 months throughout the duration of the study. Subjects will be monitored every 2 weeks by telephone and/or email.

Side effects will be evaluated using PESQ (Pediatric epilepsy Side Effects Questionnaire). This questionnaire will be administered 4 weeks, 8 weeks, and 12 weeks after baseline.

University of Colorado, Denver

Colorado Department of Public Health and Environment

Cannabis Users

Cerebral MRI and MRA

Hôpitaux Universitaires de Strasbourg

Intracranial Arterial Stenosis and Resin of Cannabis Use

Prevalence of Intracranial Arterial Stenosis in Regular Resin of Cannabis Users Compared to Control Subjects: a Preliminary Study of Feasibility

Rate on cerebral MRA the presence of cerebral Intracranial Arterial Stenosis segmental narrowing defined by at least two intra-cranial arteries compared with a cohort of non cannabis controls subjects.

Evaluate on cerebral MRI the presence of sequelae of ischemic stroke defined by a parenchymal hyperintensity in a vascular territory defined on a T2 sequence.

Evaluate a cerebral MRA at 3 months the presence of new intracranial stenosis among cannabis users, according to the prosecution or stopping use

Evaluate on cerebral MRA at 3 months reversibility stenosis present at T0 in cannabis users having stopped their consumption

stroke/marihuana

Prevalence of Strokes Secondary to a Reversible Cerebral Vasoconstriction Attributable to Cannabis Consumption in Young Subjects (≤ 45 Years) Hospitalized for an Ischaemic Stroke

The Use of Medicinal Cannabinoids as Adjunctive Treatment for Medically Refractory Epilepsy

Intracranial Arterial Stenosis and Resin of Cannabis Use

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