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[Research on effects of taurine on the transplanted tumor of mice].

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With the same forage to the mice, three experiments were done. The control group took water and experimental group took 1% taurine. 1. After the mice were vaccinated with S180 sarcoma, every group was further divided into two groups, one treated with cytoxan (CTX), another one treated with nothing.

HR-MAS MRS of the pancreas reveals reduced lipid and elevated lactate and taurine associated with early pancreatic cancer.

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The prognosis for patients with pancreatic cancer is extremely poor, as evidenced by the disease's five-year survival rate of ~5%. New approaches are therefore urgently needed to improve detection, treatment, and monitoring of pancreatic cancer. MRS-detectable metabolic changes provide useful

Effects of tumor necrosis factor alpha on taurine uptake in cultured rat astrocytes.

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Taurine is known to play a major role in volume regulation in astrocytic swelling associated with stroke and brain trauma. Apart from brain edema, the severity of brain injury is related to the levels of inflammatory cytokines such as tumor necrosis factor alpha (TNFalpha). TNFalpha had been shown

Taurine induces the apoptosis of breast cancer cells by regulating apoptosis-related proteins of mitochondria.

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Taurine (Tau), the most abundant free amino acid in humans has numerous potential health benefits through its antioxidant and anti-inflammatory properties. However, limited studies have assessed its effect on tumors and the antitumor mechanism remains unknown. The present study investigated the

Taurine: a novel tumor marker for enhanced detection of breast cancer among female patients.

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BACKGROUND The antioxidant Taurine found to display antineoplastic effect through down regulation of angiogenesis and enhancement of tumor cell apoptosis. It has been found that progressive inhibition of apoptosis and induction of angiogenesis may contribute to tumor initiation, growth and

Taurine enhances anticancer activity of cisplatin in human cervical cancer cells.

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Taurine is a nonessential amino acid and has a variety of physiological and pharmacological effects. Recently, protective effects of taurine against anticancer drugs on normal cells were investigated. But anticancer effects of taurine on cancer cells remain poorly understood. Therefore, we

Anti-Cancer Mechanisms of Taurine in Human Nasopharyngeal Carcinoma Cells.

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Taurine displays anti-tumor activity in some kinds of human cancers. However, the underlying mechanisms are poorly understood. Epstein-Barr virus-related nasopharyngeal carcinoma (NPC) is a distinctive type of head and neck cancer in Southeast Asia with the highest incidence in South China. We

RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABAA receptors involved in volume regulation.

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To identify coding and non-coding suppressor genes of anchorage-independent proliferation by efficient loss-of-function screening, we have developed a method for enzymatic production of low complexity shRNA libraries from subtracted transcriptomes. We produced and screened two LEGO (Low-complexity

Optimal Dose of Vitamin D3 400 I.U. for Average Adults has A Significant Anti-Cancer Effect, While Widely Used 2000 I.U. or Higher Promotes Cancer: Marked Reduction of Taurine & 1α, 25(OH)2D3 Was Found In Various Cancer Tissues and Oral Intake of Optimal Dose of Taurine 175mg for Average Adults, Rather Than 500mg, Was Found to Be A New Potentially Safe and More Effective Method of Cancer Treatment.

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During the past 10 years, the author had found that the optimal dose of Vitamin D3 400 I.U. has safe & effective anticancer effects, while commonly used 2000-5000 I.U. of Vit. D3 often creates a 2-3 time increase in cancer markers. We examined the concentration of Taurine in normal internal organs

Clinical Significance of Human Papillomavirus Type 16 for Breast Cancer & Adenocarcinomas of Various Internal Organs and Alzheimer's Brain with Increased β-amyloid (1-42); Combined Use of Optimal Doses of Vitamin D3 and Taurine 3 times/day Has Significant Beneficial Effects of Anti-Cancer, Anti-Ischemic Heart, and Memory & Other Brain Problems By Significant Urinary Excretion of Viruses, Bacteria, and Toxic Metals & Substances.

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Human Papillomavirus type 16 (HPV-16) has a significant role in various cancers and Alzheimer's disease. 500 breast cancer mammograms as well as 3 cases of adenocarcinomas of esophagus, stomach, colon, prostate gland, uterus, ovary that was examined had significant infection of HPV- 16 with

pH optimization for a reliable quantification of brain tumor cell and tissue extracts with (1)H NMR: focus on choline-containing compounds and taurine.

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The aim of this study was to define the optimal pH for (1)H nuclear magnetic resonance (NMR) spectroscopy analysis of perchloric acid or methanol-chloroform-water extracts from brain tumor cells and tissues. The systematic study of the proton chemical shift variations as a function of pH of 13 brain

Characterisation of taurine uptake in human KB MDR and non-MDR tumour cell lines in culture.

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Studies on taurine transport in MDR (multidrug resistant) and non-MDR KB cancer cells show that both cell types contain Na(+)- and Cl(-)-dependent high-affinity and low-affinity transport systems selective for beta-amino acids and a taurine diffusion component. Good buffers, such as HEPES or MOPS,

Tumor necrosis factor alpha stimulates taurine uptake and transporter gene expression in human intestinal Caco-2 cells.

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The effect of cytokines on the taurine uptake by human intestinal epithelial Caco-2 cells was investigated. Among the various cytokines tested, tumor necrosis factor alpha (TNF-alpha) markedly increased the taurine uptake by Caco-2 cells, resulting in an increase in the intracellular taurine level.

Modification of IkappaBalpha by taurine bromamine inhibits tumor necrosis factor alpha-induced NF-kappaB activation.

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OBJECTIVE Eosinophils play a prominent role in the pathogenesis of various common human allergic diseases, including asthma. Taurine chloramine (TauCl) and taurine bromamine (TauBr) are products of activated neutrophils and eosinophils. TauCl has strong anti-inflammatory properties. However, much

Mechanism of taurine-induced apoptosis in human colon cancer cells.

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Taurine (Tau) has been shown to possess cancer therapeutic effect through induction of apoptosis, while the underlying molecular mechanism of its anti-cancer effect is not well understood. PUMA (p53-upregulated modulator of apoptosis) plays an important role in the process of apoptosis induction in

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