Biological Availability

The volunteers will follow a low-phytochemical diet for five days, meaning that they will exclude fruits, vegetables, legumes, coffee, tea, alcoholic beverages and chocolate. On the day of the experiment and after overnight fasting, the volunteers will consume 10g of natural Mastiha and blood samples will be obtained on timepoints 0h, 30min, 1h, 2h, 4h, 6h and 24h after Mastiha intake. Until timepoint 6h, will be allowed to consume only water. Urine samples will also be collected on timepoints 0h, 4h, 8h and 24h.

Mastiha

Harokopio University

Bioavailability of the Microconstituents of Natural Chios Mastiha in Healthy Adults.

A Bioavailability Study of the Natural Chios Mastiha in Blood and Urine Samples of Healthy Adults.

Andriana C Kaliora

"Assistant Professor in Foods & Human Nutrition"

patients with clinically active ulcerative colitis undergoing colonoscopy not for study purpose, biopsy will be taken from inflamed and normal mucosa and treated with either cannabinoids or will be used as a control

patients with clinically non active ulcerative colitis undergoing colonoscopy not for study purpose, biopsy will be taken from inflamed and normal mucosa and treated with either cannabinoids or will be used as a control

patients with clinically active crohns disease undergoing colonoscopy not for study purpose, biopsy will be taken from inflamed and normal mucosa and treated with either cannabinoids or will be used as a control

patients with clinically non active crohns disease undergoing colonoscopy not for study purpose, biopsy will be taken from inflamed and normal mucosa and treated with either cannabinoids or will be used as a control

Inflammatory Bowel Disease

no intervention in patients treatment, only biopsy taken

Gastroenterology institute Meir Hospital

Cytokine Production of Colonic Tissue From IBD Patients

The Effect of Cannabinoids on Cytokine Production of Colonic Tissue From IBD Patients

different extracts of cannabis sativa will be applied to culture of biopsy and the cytokins TNF alpha, will be measured in the supernatant of the treated biopsies and compared to controls

different extracts of cannabis sativa will be applied to culture of biopsy and the cytokin IL-6, will be measured in pg/ml in the supernatant of the treated biopsies and compared to controls

different extracts of cannabis sativa will be applied to culture of biopsy and the cytokine IL-8, will be measured in pg/ml in the supernatant of the treated biopsies and compared to controls

different extracts of cannabis sativa will be applied to culture of biopsy and the cytokine IL-17, will be measured in pg/ml in the supernatant of the treated biopsies and compared to controls

different extracts of cannabis sativa will be applied to culture of biopsy and the cytokine IL-10, will be measured in pg/ml in the supernatant of the treated biopsies and compared to controls

terpenoid/biegunka

Bioavailability of the Microconstituents of Natural Chios Mastiha in Healthy Adults.

Cytokine Production of Colonic Tissue From IBD Patients

Najbardziej kompletna baza danych ziół leczniczych poparta naukowo