Acta Europaea fertilitatis
Antifertility efficacy of Catharanthus roseus Linn: a biochemical and histological study.
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Oral administration of Catharanthus roseus Linn, leaf extract caused widespread testicular necrosis, hyalinization of tubules and Sertoli cell-only-Syndrome. Biochemical studies revealing notable reduction in glycogen and fructose levels in reproductive tissues support the histological observations and confirm the antifertility properties of C. roseus extract.