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Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 1998-Dec

[Bacillus cereus septicemia in a patient with severe aplastic anemia].

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K Ueda
M Konishi
K Maeda
K Hamada
M Sakamoto
E Yoshimoto
T Majima
K Mikasa
E Kita
R Sano

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A 78-year-old female was admitted with complaints of malaise and fatigue in the legs. The patient was diagnosed as severe aplastic anemia and treatment was started with metenolone and steroid pulse therapy. Administration of antibiotics and granulocyte-colony stimulating factor which led to a resolution of the high fever. About four months after admission, the patient developed vomiting and abdominal pain with a spiking fever. The next day after suddenly losing consciousness, she died. B. cereus was isolated from blood cultures. Autopsy specimens of the liver, cardiac muscle and lung showed changes due to B. cereus. This pathogen is widely distributed in nature. We should not overlook B. cereus as a contamination, but rather should consider it a potential pathogen in immunocompromised hosts, when it is isolated from blood cultures.

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