Zeitschrift für Naturforschung - Section C Journal of Biosciences
Cassiaindoline, a new analgesic and anti-inflammatory alkaloid from Cassia alata.
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Cassiaindoline is a new dimeric indole alkaloid isolated from Cassia alata L. leaves whose structure was elucidated through spectroscopic analyses. It exhibited analgesic activity at a dosage of 125.0 mg/kg mouse and decreased the number of writhings induced by acetic acid by 49.4%. It also showed a 57.1% anti-inflammatory activity at a dosage of 75 mg/kg mouse.