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Problemy medycyny wieku rozwojowego 1975

[Frequency and natural history of several types of transpositions of the great arteries (TGA) in children (author's transl)].

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M Popczyńska-Markowa
A Jawień
S Januś

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The frequency and clinical differences between several types of TGA have been estimated. In a group of 52 patients with TGA three anatomic types were distinguished on the basis of the classification of Nadas (Fig. 1). The correlation between TGA type and sex, weight at birth, predominating clinical symptoms, most frequent clinical complications and survival time in children with this congenital malformation were investigated (Fig. 1-6). Type I was found almost five times more frequently in boys who had a higher than average weight at birth (Fig. 1-3). The most frequent clinical symtpoms were: cyanosis, early congestive heart failure and paroxysmal anoxemia (Fig. 4). Infants with this TGA type died much earlier than infants with other TGA types (Fig. 6). The frequency of type IIA was the lowest, similar in both sexes (Fig. 1). Among clinical symptoms cyanosis, paroxysmal anoxemia and systolic murmurs prevailed. No congestive heart failure was observed in this type (Fig. 4). Type IIC was more frequent in boys, but simultaneously it was the most frequent TGA type noticed in female infants (Fig. 1). Almost in all children heart murmurs were found, but only one of the examined cases with this type was affected by congestive heart failure (Fig. 4). The above-mentioned differences between clinical symptoms of several types of transposition of great arteries can be helpful when the adequate treatment is chosen.

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