Science 1974-Sep
Inert gas narcosis, the high pressure neurological syndrome, and the critical volume hypothesis.
Apenas usuários registrados podem traduzir artigos
Entrar Inscrever-se
O link é salvo na área de transferência
Palavras-chave
Resumo
The hypothesis that general anesthesia or pressure-induced convulsions occur when a hydrophobic region is expanded or compressed, respectively, by critical amounts is consistent with recent data obtained with mice. Calculations show that anesthesia occurs at an expansion of 1.1 percent and convulsions at a compression of 0.85 percent, the latter site of action being more compressible.